Opposite sex may refer to:

  • A phrase used in the discussion of sex or gender
  • Dioecy, a characteristic of a species, meaning that it has distinct male and female individual organisms
  • Heterosexuality, the romantic attraction, sexual attraction or sexual behavior between persons of the opposite sex or gender
  • The Opposite Sex, a 1956 musical film, directed by David Miller
  • The Opposite Sex (2014 film), directed by Jennifer Finnigan and Jonathan Silverman
  • Opposite Sex (album), a 1995 album by the Vulgar Boatmen
  • Opposite Sex (TV series), a 2000 TV series
  • The Opposite Sex: Rene's Story and The Opposite Sex: Jamie's Story, a 2004 two-part story which is part of the Real Momentum documentary series

See also

  • The Opposite of Sex, a 1998 romantic comedy film, written and directed by Don Roos
  • The Opposite of Sex (musical), a 2004 musical based on the screenplay to the 1998 film
  • Same sex (disambiguation)