Oconee may refer to:
Places in the United States
- Oconee, Georgia
- Oconee, Illinois
- Oconee, Nebraska
- Oconee County, Georgia
- Oconee County, South Carolina
- Oconee River, Georgia
- Oconee Township, Shelby County, Illinois
- Oconee Township, Nebraska
- Lake Oconee, Georgia
Other uses
- Oconee (tribal town), Hitchiti speakers that became part of the Seminole and Creek nations
- Oconee War, in Georgia, USA, 1780s–1790s
- Oconee Nuclear Generating Station, in South Carolina
See also
- Oconi, Ocone, or Oconee, a branch of the Timucua people in southeastern Georgia
- Oconi, Ocone, or Oconee, a town in Apalachee Province in north Florida