OSC may refer to:

Organizations

  • Odborové sdružení československé, the Czechoslovak Trade Union Association
  • Office of Special Counsel (in the United States of America)
  • Ohio Supercomputer Center, a computing research facility in Columbus
  • Ontario Science Centre, a science museum in Toronto, Canada
  • Ontario Securities Commission, a securities regulatory agency
  • Open Source Center, a United States government center that provides analysis of open-source intelligence
  • Orbital Sciences Corporation, a satellite-oriented company
  • Order of Saint Clare, a Religious Order founded by Clare of Assisi whose members use the post-nominal letters O.S.C.
  • Ordo Sanctae Crucis or Canons Regular of the Order of the Holy Cross, a Roman Catholic religious order commonly called Crosiers
  • Orlando Science Center, a science-education establishment in Florida
  • Overseas School of Colombo, a multinational English medium international school located in Colombo, Sri Lanka.

Computing

  • Open Sound Control, a music-oriented electronic communications protocol used in computers and multimedia devices
  • openSUSE Command-line tool, a command-line tool used for openSUSE build service
  • Orthogonal signal correction, a spectral preprocessing technique
  • Operating system command, one of the C0 and C1 control codes
  • Optical Signature Code, an industry standard format for LWIR signatures.

Other uses

  • Off-site construction, a mode of construction
  • Orson Scott Card (born 1951), American speculative-fiction author
  • Organic solar cell
  • Oscoda–Wurtsmith Airport (IATA code: OSC), Michigan, United States
  • Osceola (Amtrak station) (Amtrak station code: OSC), Iowa, United States
  • Order to show cause
  • Object show community, the fandom for the animated web series Battle for Dream Island