OPC may refer to:

Architecture and engineering

  • Optical proximity correction
  • Ordinary Portland cement
  • Organic Photo Conductor, an element used for, among other applications, photocopier and laser printer drums.

Computing

  • Open Packaging Conventions, a container-file technology created by Microsoft to store a combination of XML and non-XML files
  • Open Platform Communications (formerly "OLE for Process Control")
  • OPC Foundation, a related consortium
  • Operations Planning and Control, from Tivoli Software, known as IBM Tivoli Workload Scheduler
  • Optimized Power Control, a method to adjust laser power when writing optical media.
  • Other peoples' computers, reference to privacy issues of cloud computing data being on somebody else's computer rather than your own and potential security issues.

Medicine and natural sciences

  • Ocean Prediction Center
  • Oligodendrocyte precursor cell
  • Oligomeric proanthocyanidin
  • Oropharyngeal cancer

Social matters, politics and government

  • Obama Presidential Center
  • (Federal) Office for the Protection of the Constitution, a translation of the German name Bundesamt für Verfassungsschutz
  • Office of Policy Coordination, a secret U.S. government unit, 1948–1952
  • Office of the Parliamentary Counsel (United Kingdom)
  • Office of the Privacy Commissioner of Canada
  • Online Party of Canada
  • Ontario Progressive Conservative Party, Conservative political party in the province of Ontario
  • Oodua Peoples Congress, militant Yoruba nationalist organization situated in Nigeria
  • Organisation pour la prévention de la cécité (Organisation for the Prevention of Blindness), a French blindness charity working in Africa
  • Orthodox Presbyterian Church, a confessional Reformed Christian denomination
  • Ottawa People’s Commission on the Convoy Occupation, Ontario, Canada
  • Overseas Press Club, a journalists' organization in New York City
  • Overdose prevention centers, otherwise known as Supervised injection sites

Other

  • Offshore Patrol Cutter
  • Ontario Police College
  • O-Pee-Chee, a Canadian sports card company
  • Ontario Pioneer Camp, in Huntsville, Ontario, Canada
  • Opel Performance Center, a division of car manufacturer Opel
  • Optional Payment Charge, a surcharge applied when paying by credit card for airline flights
  • Organic photoconductor drum, used in photocopiers and printers