OMD may stand for:

Science

  • Osteomodulin, extracellular matrix protein
  • Organic matter digestibility
  • Organic mental disorders
  • Orofacial myological disorders, diseases affecting facial muscles
  • Oromandibular dystonia, neurological disease
  • 3-O-Methyldopa, metabolite and drug
  • Occult macular dystrophy, a rare genetic retinal disease

Entertainment and media

  • Orchestral Manoeuvres in the Dark (alternately billed as OMD), an English electronic band
  • OMD Worldwide, a global media agency network
  • Orcs Must Die!, a strategy video game
  • Spider-Man: "One More Day", a 2007 four-part Spider-Man comic book crossover storyline

Religion

  • Ordo Frati Excalceatorum de B.M.V. de Mercede, the Discalced Mercedarians, Catholic religious order
  • Clerics Regular of the Mother of God of Lucca members use the suffix of O.M.D.
  • Ohio-Meadville District

Other uses

  • Olympus OM-D series of digital cameras
  • One Million Degrees, a Chicago educational charity
  • Ormond railway station, Melbourne