Nyssa may refer to:
People
- Gregory of Nyssa (335–395), 4th-century Christian bishop, theologian, and saint
- Nyssa (Doctor Who), a fictional character in Doctor Who
- Nyssa Raatko, an adversary of the DC Comics character Batman
- Nyssa (musician), Canadian singer-songwriter
Places
- Nyssa (Alexander), a town spared by Alexander the Great in his invasion of Central Asia
- Nyssa (Cappadocia), a Roman city and bishopric
- Nyssa (Caria), a Hellenistic city, Asian Turkey
- Nyssa (Lycia), an ancient city, Asian Turkey
- Nyssa, Oregon, a city in the United States
Other
- Nyssa (plant), the genus name for tupelo trees
- New York State Snowmobile Association
- New York State Sociological Association
See also
- Neisse (disambiguation)
- Nisa (disambiguation)
- Nissa (disambiguation)
- Nisse (disambiguation)
- Nysa (disambiguation)