NPO may refer to:

Medicine

  • , Latin for 'nothing by mouth', a medical instruction to withhold oral intake of food and fluids
  • neurogenic pulmonary oedema

Science

  • North Pacific Oscillation, a teleconnection pattern in atmospheric conditions over the North Pacific
  • NP optimization problem, an optimization problem that is NP-hard
  • NPO, characterizing thermal stability of a capacitor
  • The NPO complexity class, standing for "NP-optimization problem", in computational complexity

Organisations

  • Nonprofit organization
  • National Portfolio Organisation, a UK-based culture and arts organisation receiving substantial funding from Arts Council England
  • National Ports Organisation, former part of the UK Department for Transport
  • National Preservation Office, part of the British Library
  • Scientific Production Association (, ), a form of scientific research-to-production facility in the Soviet Union and the Russian Federation.
  • ('Netherlands Public Broadcasting'), governing body of the Netherlands (Dutch) Public Broadcasting System
  • ('Dutch public broadcasting system'), the public broadcasting service in the Netherlands
  • Netherlands Pathfinder Organisation (), one of the organisations that evolved into Scouting Nederland, the national Scouting organisation
  • NPO UK Ltd., a chain of stationery and book shops in Northern Ireland, now part of Eason & Son
  • National Printing Office, one of the three recognized government printers of the Philippines
  • National Parents Organization, non-profit charitable and educational organization in the United States that promotes shared parenting.

Other

  • Nanga Pinoh Airport, Indonesia (IATA code)
  • Pochuri language, of Nagaland, India (ISO 639 code)