Nis, Niš, NiS or NIS may refer to:
Places
- Niš, a city in Serbia
- Nis, Iran, a village
- Ness, Lewis (), a village in the Outer Hebrides islands
Businesses and organizations
- Naftna Industrija Srbije, Petroleum Industry of Serbia
- Nagoya International School
- Nanjing International School
- National Institute of Science, United States
- National Institute of Sports, India
- Nazarbayev Intellectual Schools
- , railway company in the Dutch East Indies
- New Israeli Shekel, is the current currency of Israel
- Nippon Ichi Software, a video game developer
- Norwegian International School
- Norwegian International Ship Register, ()
- Nuclear Information Service, independent UK organisation
Military, intelligence and security
- National Intelligence Service (disambiguation), abbreviated NIS in some countries
- National Intelligence Service (Greece)
- National Intelligence Service (South Africa), former agency
- National Intelligence Service (South Korea)
- Norwegian Intelligence Service
- Naval Investigative Service, later Naval Criminal Investigative Service, U.S.
- Canadian Forces National Investigation Service (CFNIS; sometimes abbreviated to NIS)
Science and technology
Chemistry and biology
- Nickel sulfide (chemical symbol NiS)
- N-Iodosuccinimide, a reagent
- Sodium-iodide symporter, a protein
Computing
- Network Information Service, directory service protocol
- Network information system, for managing utilities networks
- NIS Directive, the EU Directive on Security of Network and Information Systems
Other uses
- National innovation system
- New Israeli Shekel (unofficial abbreviation), the currency of Israel
- Niš (boat), a sunk Yugoslav ferry
- Nordic Integrated System, for ski binding
- Johnson (rapper) (born 1979), Danish rapper previously known as NiggerenISlæden (N.I.S.)