NFL Series could refer to:<br/>
In American football video games:
- EA's Madden NFL series
- Sega's NFL 2K series (1999-2004)
- NFL (series), a series of games by Gameloft
In toys:
- The McFarlane Sports Picks "NFL Series" of player figures (since 2001)
- Topps' "NFL Series" of trading cards, especially popular in the early 1990s