This article lists the winners and nominees for the NAACP Image Award for Outstanding Actress in a Comedy Series. It was known as the Outstanding Lead Actress in a Comedy Series until 2000. Currently, Tracee Ellis Ross holds the record for most wins in this category, having won nine times.
Winners and nominees
Winners are listed first and highlighted in bold.
1980s
{| class="wikitable" style="width:100%;"
|- style="background:#bebebe;"
! style="width:11%;"| Year
! style="width:42%;"| Actress
! style="width:42%;"| Series
! style="width:5%;"| Ref
|-
| rowspan="2" align="center"| 1982
|- style="background:#B0C4DE"
| Marla Gibbs
| The Jeffersons
| rowspan="2" align="center"|
|-
| rowspan="2" align="center"| 1983
|- style="background:#B0C4DE"
| Marla Gibbs
| The Jeffersons
| align="center"|
|-
| align="center"| 1984 – 87
| colspan="3"
|-
| rowspan="6" align="center"| 1988
|- style="background:#B0C4DE"
| Phylicia Rashad
| The Cosby Show
| rowspan="6" align="center"|
|-
| Jasmine Guy
| A Different World
|-
| Anna Maria Horsford
| Amen
|-
| Daphne Maxwell Reid
| rowspan="2"| Frank's Place
|-
| Frances Williams
|-
| rowspan="6" align="center"| 1989
|- style="background:#B0C4DE"
| Phylicia Rashad
| The Cosby Show
| rowspan="6" align="center"|
|-
| Jasmine Guy
| A Different World
|-
| Anna Maria Horsford
| Amen
|-
| Daphne Maxwell Reid
| rowspan="2"| Frank's Place
|-
| Frances Williams
|}
1990s
{| class="wikitable" style="width:100%;"
|- style="background:#bebebe;"
! style="width:11%;"| Year
! style="width:42%;"| Actress
! style="width:42%;"| Series
! style="width:5%;"| Ref
|-
| rowspan="2" align="center"| 1990
|- style="background:#B0C4DE"
| Jasmine Guy
| A Different World
| align="center"|
|-
| align="center"| 1991
| colspan="3"
|-
| rowspan="6" align="center"| 1992
|- style="background:#B0C4DE"
| Jasmine Guy
| A Different World
| rowspan="6" align="center"|
|-
| Janet Hubert-Whitten
| Fresh Prince of Bel Air
|-
| Phylicia Rashad
| The Cosby Show
|-
| Cree Summer
| A Different World
|-
| Raven-Symoné
| The Cosby Show
|-
| rowspan="2" align="center"| 1993
|- style="background:#B0C4DE"
| Jasmine Guy
| A Different World
| rowspan="2" align="center"|
|-
| rowspan="6" align="center"| 1994
|- style="background:#B0C4DE"
| Jasmine Guy
| A Different World
| rowspan="6" align="center"|
|-
| Ella Joyce
| Roc
|-
| Erika Alexander
| rowspan="2"| Living Single
|-
| Queen Latifah
|-
| Tisha Campbell-Martin
| Martin
|-
| align="center"| 1995
| colspan="3"
|-
| rowspan="6" align="center"| 1996
|- style="background:#B0C4DE"
| Erika Alexander
| Living Single
| rowspan="6" align="center"|
|-
| Tisha Campbell-Martin
| Martin
|-
| Kim Coles
| rowspan="3"| Living Single
|-
| Kim Fields
|-
| Queen Latifah
|-
| rowspan="6" align="center"| 1997
|- style="background:#B0C4DE"
| Phylicia Rashad
| Cosby
| rowspan="6" align="center"|
|-
| Tisha Campbell-Martin
| Martin
|-
| Erika Alexander
| rowspan="3"| Living Single
|-
| Kim Coles
|-
| Queen Latifah
|-
| rowspan="5" align="center"| 1998
|- style="background:#B0C4DE"
| Kim Coles
| Living Single
| rowspan="5" align="center"|
|-
| Brandy
| Moesha
|-
| Queen Latifah
| Living Single
|-
| Phylicia Rashad
| Cosby
|-
| rowspan="6" align="center"| 1999
|- style="background:#B0C4DE"
| Tia Mowry and Tamera Mowry
| Sister, Sister
| rowspan="6" align="center"|
|-
| Brandy
| Moesha
|-
| Vivica A. Fox
| Getting Personal
|-
| Pam Grier
| Linc's
|-
| Holly Robinson Peete
| For Your Love
|}
2000s
{| class="wikitable" style="width:100%;"
|- style="background:#bebebe;"
! style="width:11%;"| Year
! style="width:42%;"| Actress
! style="width:42%;"| Series
! style="width:5%;"| Ref
|-
| rowspan="6" align="center"| 2000
|- style="background:#B0C4DE"
| Tia Mowry and Tamera Mowry
| Sister, Sister
| rowspan="6" align="center"|
|-
| Brandy
| Moesha
|-
| Pam Grier
| Linc's
|-
| Elise Neal
| The Hughleys
|-
| Holly Robinson Peete
| For Your Love
|-
| rowspan="6" align="center"| 2001
|- style="background:#B0C4DE"
| Mo'Nique
| The Parkers
| rowspan="6" align="center"|
|-
| Brandy
| Moesha
|-
| Elise Neal
| The Hughleys
|-
| Wendy Raquel Robinson
| The Steve Harvey Show
|-
| Holly Robinson Peete
| For Your Love
|-
| rowspan="6" align="center"| 2002
|- style="background:#B0C4DE"
| Mo'Nique
| The Parkers
| rowspan="6" align="center"|
|-
| Tisha Campbell-Martin
| My Wife and Kids
|-
| Tracee Ellis Ross
| Girlfriends
|-
| Wendy Raquel Robinson
| The Steve Harvey Show
|-
| Holly Robinson Peete
| For Your Love
|-
| rowspan="6" align="center"| 2003
|- style="background:#B0C4DE"
| Tisha Campbell Martin
| My Wife and Kids
| rowspan="6" align="center"|
|-
| Golden Brooks
| rowspan="2"| Girlfriends
|-
| Tracee Ellis Ross
|-
| Mo'Nique
| The Parkers
|-
| Kellita Smith
| The Bernie Mac Show
|-
| rowspan="6" align="center"| 2004
|- style="background:#B0C4DE"
| Mo'Nique
| The Parkers
| rowspan="6" align="center"|
|-
| Tisha Campbell-Martin
| My Wife and Kids
|-
| Tracee Ellis Ross
| Girlfriends
|-
| Whoopi Goldberg
| Whoopi
|-
| Kellita Smith
| The Bernie Mac Show
|-
| rowspan="6" align="center"| 2005
|- style="background:#B0C4DE"
| Mo'Nique
| The Parkers
| rowspan="6" align="center"|
|-
| Tisha Campbell-Martin
| My Wife and Kids
|-
| Tracee Ellis Ross
| Girlfriends
|-
| Eve
| Eve
|-
| Kellita Smith
| The Bernie Mac Show
|-
| rowspan="6" align="center"| 2006
|- style="background:#B0C4DE"
| Tichina Arnold
| Everybody Hates Chris
| rowspan="6" align="center"|
|-
| Tracee Ellis Ross
| rowspan="2"| Girlfriends
|-
| Jill Marie Jones
|-
| Holly Robinson Peete
| Love, Inc.
|-
| Rachel True
| Half & Half
|-
| rowspan="6" align="center"| 2007
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Girlfriends
| rowspan="6" align="center"|
|-
| Tichina Arnold
| Everybody Hates Chris
|-
| America Ferrera
| Ugly Betty
|-
| Maya Rudolph
| Saturday Night Live
|-
| Raven-Symoné
| That's So Raven
|-
| rowspan="6" align="center"| 2008
|- style="background:#B0C4DE"
| America Ferrera
| Ugly Betty
| rowspan="6" align="center"|
|-
| Tichina Arnold
| Everybody Hates Chris
|-
| Golden Brooks
| Girlfriends
|-
| Tracee Ellis Ross
| Girlfriends
|-
| Tia Mowry
| The Game
|-
| rowspan="6" align="center"| 2009
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Girlfriends
| rowspan="6" align="center"|
|-
| Tichina Arnold
| Everybody Hates Chris
|-
| Cassi Davis
| Tyler Perry's House of Payne
|-
| America Ferrera
| Ugly Betty
|-
| Tia Mowry
| The Game
|}
2010s
{| class="wikitable" style="width:100%;"
|- style="background:#bebebe;"
! style="width:11%;"| Year
! style="width:42%;"| Actress
! style="width:42%;"| Series
! style="width:5%;"| Ref
|-
| rowspan="6" align="center"| 2010
|- style="background:#B0C4DE"
| Cassi Davis
| Tyler Perry's House of Payne
| rowspan="6" align="center"|
|-
| Tichina Arnold
| Everybody Hates Chris
|-
| America Ferrera
| Ugly Betty
|-
| C. C. H. Pounder
| Brothers
|-
| Sherri Shepherd
| Sherri
|-
| rowspan="6" align="center"| 2011
|- style="background:#B0C4DE"
| Vanessa Williams
| Desperate Housewives
| rowspan="6" align="center"|
|-
| Tatyana Ali
| Love That Girl!
|-
| Essence Atkins
| Are We There Yet?
|-
| Cassi Davis
| Tyler Perry's House of Payne
|-
| Salli Richardson-Whitfield
| Eureka
|-
| rowspan="6" align="center"| 2012
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Reed Between the Lines
| rowspan="6" align="center"|
|-
| Tatyana Ali
| Love That Girl!
|-
| Tia Mowry
| rowspan="2"| The Game
|-
| Wendy Raquel Robinson
|-
| Vanessa Williams
| Desperate Housewives
|-
| rowspan="6" align="center"| 2013
|- style="background:#B0C4DE"
| Cassi Davis
| Tyler Perry's House of Payne
| rowspan="6" align="center"|
|-
| Tatyana Ali
| Love That Girl!
|-
| Amber Riley
| Glee
|-
| Wendy Raquel Robinson
| The Game
|-
| Kellita Smith
| The First Family
|-
| rowspan="6" align="center"| 2014
|- style="background:#B0C4DE"
| Wendy Raquel Robinson
| The Game
| rowspan="6" align="center"|
|-
| Mindy Kaling
| The Mindy Project
|-
| Niecy Nash
| The Soul Man
|-
| Tasha Smith
| Tyler Perry's For Better or Worse
|-
| Aisha Tyler
| Archer
|-
| rowspan="6" align="center"| 2015
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Black-ish
| rowspan="6" align="center"|
|-
| Uzo Aduba
| Orange Is the New Black
|-
| Mindy Kaling
| The Mindy Project
|-
| Niecy Nash
| The Soul Man
|-
| Wendy Raquel Robinson
| The Game
|-
| rowspan="6" align="center"| 2016
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Black-ish
| rowspan="6" align="center"|
|-
| Uzo Aduba
| Orange Is the New Black
|-
| Loretta Devine
| The Carmichael Show
|-
| Wendy Raquel Robinson
| The Game
|-
| Gina Rodriguez
| Jane the Virgin
|-
| rowspan="6" align="center"| 2017
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Black-ish
| rowspan="6" align="center"|
|-
| Uzo Aduba
| Orange Is the New Black
|-
| Niecy Nash
| The Soul Man
|-
| Issa Rae
| Insecure
|-
| Keesha Sharp
| Lethal Weapon
|-
| rowspan="6" align="center"| 2018
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Black-ish
| rowspan="6" align="center"|
|-
|-
| Danielle Brooks
| Orange Is the New Black
|-
| Issa Rae
| Insecure
|-
| Loretta Devine
| The Carmichael Show
|-
| Niecy Nash
| Claws
|-
| rowspan="6" align="center"| 2019
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Black-ish
| rowspan="6" align="center"|
|-
| Danielle Brooks
| Orange Is the New Black
|-
| Logan Browning
| Dear White People
|-
| Issa Rae
| Insecure
|-
| Yara Shahidi
| Grown-ish
|}
2020s
{| class="wikitable" style="width:100%;"
|- style="background:#bebebe;"
! style="width:11%;"| Year
! style="width:42%;"| Actress
! style="width:42%;"| Series
! style="width:5%;"| Ref
|-
| rowspan="6" align="center"| 2020
|- style="background:#B0C4DE"
| Tracee Ellis Ross
| Black-ish
| rowspan="6" align="center"|
|-
| Logan Browning
| Dear White People
|-
| Tiffany Haddish
| The Last O.G.
|-
| Jill Scott
| First Wives Club
|-
| Yara Shahidi
| Grown-ish
|-
| rowspan="6" align="center"| 2021
|- style="background:#B0C4DE"
| Issa Rae
| Insecure
| rowspan="6" align="center"|
|-
| Tracee Ellis Ross
| Black-ish
|-
| Regina Hall
| Black Monday
|-
| Folake Olowofoyeku
| Bob Hearts Abishola
|-
| Yara Shahidi
| Grown-ish
|-
| rowspan="6" align="center"| 2022
|- style="background:#B0C4DE"
| Issa Rae
| Insecure
| rowspan="6" align="center"|
|-
| Loretta Devine
| Family Reunion
|-
| Regina Hall
| Black Monday
|-
| Tracee Ellis Ross
| Black-ish
|-
| Yvonne Orji
| Insecure
|-
|}
Multiple wins and nominations
Wins
; 9 wins
- Tracee Ellis Ross
; 4 wins
- Mo'Nique
- Jasmine Guy
; 3 wins
- Phylicia Rashad
; 2 wins
- Cassi Davis
- Tamera Mowry
- Tia Mowry
- Issa Rae
Nominations
; 17 nominations
- Tracee Ellis Ross
; 7 nominations
- Wendy Raquel Robinson
; 6 nominations
- Tisha Campbell-Martin
- Jasmine Guy
; 5 nominations
- Tichina Arnold
- Mo'Nique
- Tia Mowry
- Issa Rae
- Phylicia Rashad
- Holly Robinson Peete
; 4 nominations
- Brandy
- Cassi Davis
- America Ferrera
- Niecy Nash
- Kellita Smith
; 3 nominations
- Uzo Aduba
- Erika Alexander
- Tatyana Ali
- Kim Coles
- Loretta Devine
- Queen Latifah
- Yara Shahidi
; 2 nominations
- Golden Brooks
- Logan Browning
- Pam Grier
- Regina Hall
- Mindy Kaling
- Tamera Mowry
- Elise Neal
- Raven-Symoné
- Vanessa Williams