Middletown is a city in Des Moines County, Iowa, United States. The population was 363 at the time of the 2020 census. It is part of the Burlington, IA–IL Micropolitan Statistical Area.
History
Middletown was laid out in 1846. In 1940, the Iowa Army Ammunition Plant was established just to the south of Middletown.
Geography
thumb|A butterfly sanctuary, planted with wildflowers, in Middletown
According to the United States Census Bureau, the city has a total area of , all land.