The Medical Scientist Training Programs (MSTPs) are dual-degree training programs that streamline the education towards both clinical (typically MD) and research doctoral degrees. MSTPs are offered by some United States medical schools, who are awarded financial support from the National Institute of General Medical Sciences, a branch of the National Institutes of Health (NIH). The goal of these training programs is to produce physician scientists who can translate laboratory discoveries into effective treatments for patients.
The NIH began awarding the MSTP designation in 1964. Albert Einstein College of Medicine, Northwestern University, and New York University were the original three MSTP programs that were established. As of 2024, there were 58 NIH-funded MSTP programs in the US (56 MD-PhD, 4 DVM-PhD), supporting over 1000 students at all stages of the program.
History
The program has its origins in the non-NIH funded MD-PhD training offered at the nation's research-centric medical schools. An early dual-degree program began at Case Western Reserve University School of Medicine in 1956. Other prominent medical schools quickly followed this example and developed integrated MD-PhD training structures.
In 1964, the NIH created the Medical Scientist Training Program to begin funding this medical and research education. Albert Einstein College of Medicine, Northwestern University, and New York University were the original three MSTP programs that were established.
In 2022, the NIH announced the Leading Equity and Advancing Diversity in the Medical Scientist Training Program (LEAD MSTP). The LEAD MSTP shares a similar goal to the MSTP by supporting dual-degree training programs, but at institutions that have not historically been well represented among NIH-funded MSTPs. LEAD MSTP awards are limited to programs at historically Black colleges and universities, tribal colleges and universities, and institutions in Institutional Development Award (IDeA)-eligible states. The first LEAD MSTP program was established at the University of Nebraska Medical Center in 2024. As of 2025, there are 2 NIH-funded LEAD MSTP programs in the US.
Admissions
Admission to MSTPs is the most competitive of all graduate medical education programs in the country.
In 2018, 672 of 1855 total applicants successfully matriculated into MD-PhD programs (36.2%), but only 513 of these slots were at MSTPs, making the matriculation rate for MSTPs nationally 27.7%.
In comparison, MD-only programs had 40,174 positions for a total of 95,797 applicants (a 41.9% matriculation rate). At each institution, these acceptance rates are varied and are often far more competitive than the national data. Applicants must have very strong MCAT scores and GPAs to be considered for positions in MSTP. Reflecting this fact, from 2018 to 2019 the average GPA and MCAT for matriculants to MSTPs were 3.79 and 515.6, respectively. MSTP applicants will often have very strong research experience as well, in addition to the typical qualifications required from MD-only applicants.
Interviews for admissions at MSTPs tend to focus on the applicant's career goals and past experiences in scientific research. These may include short research talks or presentations followed by rigorous questioning by an interviewer or interviewing committee. MSTP applicants are often required to demonstrate a deep understanding of their past research projects. Multiple interview sessions conducted by different interviewers that last for 2 days are very common. At some MSTPs, applicants may also be required (or be offered the chance) to interview with the MD-only program.
Financial support
MSTP matriculants receive substantial financial awards that make them financially competitive to their MD-only counterparts even with the longer training periods. These allowances cover all tuition expenses, provide travel and supply allowances, and accommodate living expenses through an annual stipend (ranging from $26,000 to $39,000). Overall grants typically range from $600,000 - $1,000,000. These monetary awards compare to approximately $250,000 of pre-tax income.
Since MSTP grants are a type of National Research Service Award, students must be nationals (citizens or noncitizens) of the United States or possess a I-151 or I-551 alien registration receipt. However many MSTPs offer non-MSTP grant funded positions, allowing for non-citizens and non-legalized nationals to be accepted into the MD-PhD program at that particular school. These programs are indistinguishable between the students besides the funding source. Furthermore, many non-MSTP medical schools have MD-PhD programs that are not supported by the NIH but offer similar training opportunities and grant stipends.
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| Baylor College of Medicine
| 1976
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| Case Western Reserve University
| 1975
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| Columbia University
| 1969
| Memorial Sloan-Kettering Cancer Center and The Rockefeller University (Tri-Institutional MD-PhD Program)
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| Duke University
| 1966
| Purdue University
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| Johns Hopkins University
| 1975
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| Medical College of Wisconsin
| 2010
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| Medical University of South Carolina
| 1999
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| Mount Sinai School of Medicine
| 1976
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| Penn State University
| 2016
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| Stanford University
| 1968
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| Tufts University
| 1994
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|University of California, Davis
|2020
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| University of California, Irvine
| 1999
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| University of California, Los Angeles
| 1983
| Cincinnati Children's Hospital Medical Center
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| University of Colorado Denver
| 1993
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| University of Iowa
| 1976
|Stowers Institute for Medical Research
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| University of Maryland, Baltimore
| 2010
| University of Maryland, College Park, NIH Intramural Research Program
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| University of Massachusetts
| 2013
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| University of Miami
| 2017
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| University of Michigan
| 1980
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| University of North Carolina at Chapel Hill
| 1999
|North Carolina State University
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| University of Pennsylvania
| 1969,
| Children’s Hospital of Philadelphia
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| University of Pittsburgh
| 1987
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| Washington University in St. Louis
| 1969
Applicants for NIH research grants that completed an MSTP program were three times more likely to be successfully funded than graduates with an MD/PhD that did not participate in an MSTP program. Internationally, there are 34 non-US institutions that provide MD–PhD training.
See also
- American Physician Scientists Association
Notes
References
External links
- NIH Overview
- American Physician Scientists Association
- List of NIH MSTPs