The median aperture (median aperture of fourth ventricle or foramen of Magendie) is an opening at the caudal portion of the roof of the fourth ventricle. It allows the flow of cerebrospinal fluid (CSF) from the fourth ventricle into the cisterna magna. The other openings of the fourth ventricle are the lateral apertures - one on either side.

Eponym

The foramen of Magendie is named for François Magendie, who first described it. The term "foramen of Magendie" is commonly used, and this opening is frequently described and illustrated as a foramen in the inferior roof of the fourth ventricle. However, the opening is an aperture, rather than a foramen.