McKinney's Cotton Pickers were an American jazz band, founded in Detroit, Michigan, United States in 1926, and led by Bill McKinney, who expanded his Synco Septet to ten players. Cuba Austin took over for McKinney on drums, with the latter becoming the band's manager. and he assembled a band. John Nesbitt helped Redman with arrangements and rehearsals. The band in 1928 included Cuba Austin (drums and vocals), Langston Curl (trumpet), Ralph Escudero (tuba), Claude Jones, Redman (clarinet, alto saxophone, baritone saxophone, vocals), Todd Rhodes (piano, celeste), Prince Robinson (clarinet, tenor saxophone), Milton Senior (trombone), George Thomas (clarinet, alto saxophone, tenor saxophone, vocals) and Dave Wilborn (banjo, vocals).

Other band members included George Bias (vocals), Benny Carter (clarinet, alto saxophone), Doc Cheatham (trumpet), Bill Coti (vocals), Ed Cuffee (trombone), Lois Deppe (vocals), Jimmy Dudley (clarinet, tenor saxophone), Robert Inge (clarinet, (alto saxophone), Quentin Jackson (trombone), Moxey-Hilton Jefferson (clarinet, alto saxophone), James P. Johnson (piano), Buddy Lee (trumpet), Donald King (vocals), Frank Marvin (vocals), Theodore McCord (clarinet, tenor saxophone), Jim Napier (vocals), Rex Stewart (cornet), and Billy Taylor (tuba). Towards the end of 1929, multiple soloists who were not regular members of the band sat in for a series of recordings. These included Leonard Davis (trumpet), Sidney de Paris (trumpet), Coleman Hawkins (clarinet, tenor saxophone), Fats Waller (piano, celeste), Joe "Fox" Smith (trumpet, cornet), and Kaiser Marshall (drums).

In 1931, Redman left to form a band and was replaced by Benny Carter.