McDonald Island or MacDonald Island may refer to
- McDonald Islands, part of Heard Island and McDonald Islands group, a remote territory administered by Australia in the southern Indian Ocean
- McDonald Island (California), in San Joaquin County on the San Joaquin River
- McDonald Island (Ontario), in the St. Lawrence River
- MacDonald Island, in British Columbia
- MacDonald Island Park, 2014 arena for The National curling tournament in Fort McMurray, Alberta, Canada
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- McDonald Island (Alaska), in Frederick Sound near Petersburg
- McDonald Island (Georgia), in Charlton County in the Okefenokee Swamp
- McDonald Island (Illinois), in the Mississippi River in southern Adams County and northern Pike County.
- McDonald Island (Michigan), a low island in the delta off the St. Clair River, within the St. Clair Flats State Wildlife Area.
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