Matobo can refer to:
- Matobo National Park in Zimbabwe
- Matobo District, an administrative division of Zimbabwe
- Matobo, Botswana, a village in Botswana
Fictional places:
- the Republic of Matobo, a fictional country from the movie The Interpreter
- Matobo, a fictional country from the Swedish comedy ' ("Morgan Pålsson - world reporter").