MPIO may refer to:
Science and technology
- Multipath I/O, in computer storage
- Mpio or MPIO, a former Korean electronics manufacturer
- Micron-sized particles of iron oxide, see Olfactory ensheathing cell#Labeling OECs
Other uses
- Max Planck Institute for Ornithology, a former research institution in Bavaria, Germany
See also
- MIMO, in radio