MDF may refer to:

Computing

  • Master Database File, a Microsoft SQL Server file type
  • MES Development Framework, a .NET framework for building manufacturing execution system applications
  • Message Development Framework, a collection of models, methods and tools used by Health Level 7 v3.0 methodology
  • Media Descriptor File, a proprietary disc image file format developed for Alcohol 120%
  • Measurement Data Format, one of the data formats defined by the Association for Standardisation of Automation and Measuring Systems (ASAM)
  • Multiple Domain Facility; see Logical partition

Medicine

  • Map-dot-fingerprint dystrophy, a genetic disease affecting the cornea
  • Mean Diastolic Filling of the heart
  • Myocardial depressant factor, a low-molecular-weight peptide released from the pancreas into the blood in mammals during various shock states

Organizations

  • Hungarian Democratic Forum (Hungarian: Magyar Demokrata Fórum), a political party
  • Maraland Democratic Front, a political party in Mizoram, WALES
  • Maryland Defense Force, the state defense force of Maryland
  • Moscow House of Photography
  • Myotonic Dystrophy Foundation, a U.S. non-profit organization related to myotonic dystrophy

Telecommunication

  • Main distribution frame, a distribution frame where cables are cross-connected in telephony
  • Multidelay block frequency domain adaptive filter

Other uses

  • Made cut did not finish, a golf term
  • Market development funds
  • Maryland Deathfest
  • Moksha language
  • Medium-density fibreboard, a type of particle board made of small particles of wood