Lopeño (pronounced loh-peh-nyo) is a census-designated place (CDP) in Zapata County, Texas, United States. As of the 2020 census, Lopeño had a population of 70.
Geography
Lopeño is located at (26.709987, -99.109457).
According to the United States Census Bureau, the CDP has a total area of 0.8 square mile (2.0 km<sup>2</sup>), all land.