Little Mac is the main character from the Punch-Out!! video game series.
Little Mac may also refer to:
People
- George B. McClellan (1826–1885), American Civil War general and politician
- Joe McEwing (born 1973), American former Major League Baseball player
- Little Mack Simmons (1933–2000), American blues harmonica player and singer
Places
- Little Mac Ski Hill, a ski area in Mackenzie, British Columbia
See also
- Big Mac (disambiguation)
- Mac (disambiguation)