Little Dixie may refer to:
Regions
- Little Dixie (Missouri)
- Little Dixie (Oklahoma)
Communities
- Little Dixie, Arkansas, an unincorporated community in Arkansas on the Woodruff-Prairie county line
- Little Dixie, Kentucky, also known as Dixiefield, in Henderson County, Kentucky
Media
- Little Dixie (film), a 2023 American crime thriller film directed by John Swab