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thumb|right|250px|Location of Oklahoma on the U.S. map
The following are people who were either born, raised, or have lived for a significant period of time in the U.S. state of Oklahoma.
Actors, directors, screenwriters, and producers
- Suzy Amis (born 1962), actress
- Erika Anderson (born 1963), actress
- Lou Antonio (born 1934), actor
- Royce D. Applegate (1939–2003), actor (sea Quest DSV)
- Gene Autry (1907–1998), actor, musician, Major League Baseball team owner
- Nicki Aycox (1975–2022), actress (Cold Case)
- Marshall Bell (born 1942), actor (G vs E)
- William Boyd (1895–1972), actor (Hopalong Cassidy)
- Zach Bryan (born 1996), singer, songwriter
- Gary Busey (born 1944), actor (The Buddy Holly Story)
- T. V. Carpio (born 1981), actress, singer
- Irene Champlin (1931–1990), actress (Flash Gordon)
- Greyson Chance (born 1997), singer
- Lon Chaney Jr (1906–1973), actor (The Wolf Man, Of Mice and Men)
- Lonny Chapman (1920–2007), actor
- Maree Cheatham (born 1942), actress (Days of Our Lives)
- Kristin Chenoweth (born 1968), Tony Award-winning actress (Wicked)
- Danny Cooksey (born 1975), actor, voice actor (Diff'rent Strokes)
- Candy Clark (born 1947), actress (American Graffiti)
- Larry Clark (born 1943), filmmaker (Kids, Ken Park), photographer
- Patrick Cranshaw (1919–2005), actor (AfterMASH)
- Joan Crawford (1906–1977), Academy Award-winning actress
- Burr DeBenning (1936–2003), actor
- Michael Dolan (born 1965), actor
- Richard Erdman (1925–2019), actor
- Blake Edwards (1922–2010), director, writer, producer, The Pink Panther, Breakfast at Tiffany's
- Glenda Farrell (1904–1971), actress (Torchy Blane)
- Kay Francis (1905–1968), actress
- James Garner (1928–2014), actor (The Rockford Files, Maverick, The Great Escape, The Notebook)
- Bill Hader (born 1978), actor, writer, comedian (SNL)
- Sterlin Harjo (born 1979), Native American filmmaker
- Chasen Hampton (born 1975), actor on Disney's The All New Mickey Mouse Club, The X-Files
- Van Heflin (1908–1971), Academy Award-winning actor
- Mark Holton (born 1958), actor
- Darla Hood (1931–1979), actress (Darla from The Little Rascals), Leedey
- Clint Howard (born 1959), actor (brother of Ron Howard)
- Jean Speegle Howard (1927–2000), actress, mother of Ron Howard
- Rance Howard (1928–2017), actor, father of Ron and Clint Howard
- Ron Howard (born 1954), director, producer, actor
- Ben Johnson (1918–1996), Academy Award-winning actor
- Jennifer Jones (1919–2009), actress (The Towering Inferno, Duel in the Sun)
- Olivia Jordan (born 1988), actress, beauty pageant winner
- Christian Kane (born 1974), actor, singer (Leverage)
- Wright King (1923–2018), actor, native of Okmulgee
- Heather Langenkamp (born 1964), actress (A Nightmare on Elm Street)
- Tracy Letts (born July 4, 1965), Pulitzer Prize for Drama, Tony Award for Best Play, Tony Award for Best Actor in a Play
- Jason London (born 1972), actor (Wildfire)
- Dick Lowry (born 1944), director
- Thad Luckinbill (born 1975), actor (The Young and the Restless)
- Terrence Malick (born 1943), film director
- April March (born 1935), burlesque dancer
- James Marsden (born 1973), actor (X-Men)
- Rue McClanahan (1934–2010), actress (The Golden Girls)
- Hayley McFarland (born 1991), actress (Lie to Me)
- Beverlee McKinsey (1938–2008), soap-opera actress
- Ryan Merriman (born 1983), actor (The Pretender)
- Vera Miles (born 1930), actress (The Searchers, Psycho)
- Sharron Miller, Emmy Award-winning director, writer, producer
- Tom Mix (1880–1940), cowboy star of silent films
- Megan Mullally (born 1958), actress, dancer, singer (Will & Grace)
- Olivia Munn (born 1980), actress, television personality (The Daily Show, The Newsroom)
;N–Z
- Clarence Nash (1904–1985), voice of Donald Duck
- Tim Blake Nelson (born 1964), actor, director (O Brother, Where Art Thou?, The Grey Zone)
- Chuck Norris (1940–2026), actor, martial artist (Walker, Texas Ranger)
- Kelli O'Hara (born 1976), Broadway actress
- Lee Pace (born 1979), actor, The Hobbit: The Desolation of Smaug
- Kinga Philipps (born 1976), actress, television personality
- Cindy Pickett (born 1947), actress (St. Elsewhere, Ferris Bueller's Day Off)
- Brad Pitt (born 1963), actor and producer
- Mary Kay Place (born 1947), actress (The Big Chill)
- Wiley Post (1898–1935), pilot, the first to travel around the world solo
- Megyn Price (born 1971), actress (Rules of Engagement)
- Tony Randall (1920–2004), actor (The Odd Couple)
- Robert Reed (1932–1992), actor (The Brady Bunch), grew up in Muskogee, Oklahoma
- Erik Rhodes (1906–1990), actor, singer
- Dale Robertson (1923–2013), film and television actor; later rancher near Yukon, Oklahoma
- Will Rogers (1875–1935), actor, columnist, radio personality
- Chelcie Ross (born 1942), actor
- Will Sampson (1933–1987), artist, actor (One Flew Over the Cuckoo's Nest)
- Gailard Sartain (born 1946), actor, artist, comedian (Hee Haw, The Buddy Holly Story)
- Tobe Sexton (born 1968), actor, filmmaker, singer, dancer (Freddy's Dead: The Final Nightmare, Offerings)
- Ted Shackelford (born 1946), actor (Knots Landing)
- Paul Sparks (born 1971), actor (Boardwalk Empire, House of Cards)
- G. D. Spradlin (1920–2011), actor (The Godfather Part II)
- Lauren Stamile (born 1976), actress (Grey's Anatomy)
- Wes Studi (born 1947), actor (Dances with Wolves, Avatar)
- Maria Tallchief (1925–2013), ballerina
- Paula Trickey (born 1966), actress (Pacific Blue)
- Jeanne Tripplehorn (born 1963), actress (Basic Instinct, Big Love)
- Countess Vaughn (born 1978), actress (The Parkers)
- Heather Wahlquist (born 1977), actress
- Susan Watson (born 1938), actress
- Randy Wayne (born 1981), actor
- Dennis Weaver (1924–2006), actor (Gunsmoke, McCloud)
- Elmo Williams (1913–2015), Academy Award-winning film editor
- Michael Wilson (1914–1978), Academy Award-winning screenwriter
- Alfre Woodard (born 1952), Academy Award-nominated, Golden Globe Award-winning actress
- Gretchen Wyler (1932–2007), actress
Athletes
<!---ALPHA please, that means A-to-Z by last name--->
;A–G
- Lane Adams (born 1989), outfielder for the Atlanta Braves
- Xavier Adibi (born 1984), linebacker for Houston Texans
- Troy Aikman (born 1966), quarterback, OU, UCLA and Dallas Cowboys, Pro Football Hall of Fame inductee, sportscaster
- Brent Albright (born 1978), professional wrestler
- Brett Anderson (born 1988), pitcher for the Oakland Athletics
- Mark Anderson (born 1983), defensive end for the Buffalo Bills
- Kelenna Azubuike (born 1983), shooting guard/small forward for the New York Knicks
- David Baas (born 1981), guard and center for New York Giants
- Alvin Bailey (born 1991), offensive lineman for the Seattle Seahawks
- Dan Bailey (born 1988), placekicker for Dallas Cowboys
- Billy Bajema (born 1982), tight end for Baltimore Ravens
- Jeff Banister (born 1964), MLB catcher, manager of Texas Rangers
- Dallas Beeler (born 1989), pitcher for Chicago Cubs
- Christopher Bell (born 1994), NASCAR Cup Series driver
- Johnny Bench (born 1947), MLB catcher for Cincinnati Reds, member Baseball Hall of Fame
- Al Benton (1911–1968), MLB pitcher
- Tanner Berryhill (born 1993), Monster Energy NASCAR Cup Series driver
- Nick Blackburn (born 1982), starting pitcher for Minnesota Twins
- Douglas Blubaugh (1934–2011), Olympic gold medalist in freestyle wrestling
- Brian Bosworth (born 1965), OU and NFL player
- Sam Bradford (born 1987), football quarterback, OU and Minnesota Vikings
- Archie Bradley (born 1992), pitcher for the Arizona Diamondbacks
- Jack Brisco (1941–2010), professional wrestler
- Jerry Brisco (born 1946), professional wrestler
- Louise Brough (1923–2014), Hall of Fame tennis player
- Josh Brown (born 1979), placekicker for New York Giants
- Mike Brumley (born 1963), third base coach for Seattle Mariners
- Ryan Budde (born 1979), catcher for Arizona Diamondbacks
- Bruce Buffer (born 1957), Octagon announcer for UFC main events
- Mikey Burnett (born 1974), UFC fighter
- Sol Butler (1895–1954), athlete who competed in football and track and field
- Patrick Callan (born 1999), competitive swimmer
- Joe Carter (born 1960), Major League Baseball outfielder
- Sherri Coale (born 1965), women's basketball coach at OU
- Charles Coe (1923–2001), U.S. Amateur golfer, won seven titles
- Larry Coker (born 1948), football coach at University of Miami
- Nick Cole (born 1984), guard for Philadelphia Eagles
- Nadia Comăneci (born 1961), five-time Olympic gold medalist gymnast
- Bart Conner (born 1958), Olympic gold medal gymnast
- Riley Cooper (born 1987), wide receiver for Philadelphia Eagles
- Bobby Cox (born 1941), Baseball Hall of Fame manager for Atlanta Braves
- Kendall Cross (born 1968), Olympic gold medalist in freestyle wrestling
- Harold DeMarsh (1902–1982), first ever NCAA Wrestling champion
- Don Demeter (born 1935), Major League Baseball outfielder
- Phillip Dillard (born 1986), linebacker for UFL's Omaha Nighthawks
- Jay Thomas Evans (1931–2008), Olympic silver medalist in freestyle wrestling
- Tim Flannery (born 1957), MLB infielder and coach
- Ross Flood (1910–1995), Olympic silver medalist in freestyle wrestling
- Brian Flynn (born 1990), pitcher for Kansas City Royals
- Ryan Franklin (born 1977), pitcher for Baltimore Orioles
- Dominique Franks (born 1987), cornerback for Atlanta Falcons
- Edward C. Gallagher (1887–1940), champion OSU sprinter and football player, track and wrestling coach; winningest wrestling coach in NCAA history, 11 NCAA titles, Olympic wrestling coach, National Wrestling Hall of Fame charter member
- Vickie Gates (born 1962), IFBB professional bodybuilder
- Koda Glover (born 1993), pitcher for Washington Nationals
- Bill Goldberg (born 1966), professional NFL football player and undefeated professional wrestler
- Kelly Gregg (born 1976), OU and NFL player
- Jermaine Gresham (born 1988), tight end for Arizona Cardinals
- Matt Grice (born 1981), UFC fighter
- Blake Griffin (born 1989), power forward for Detroit Pistons
- Taylor Griffin (born 1986), pro basketball player
;H–M
- Charlie Haas (born 1972), WWE professional wrestler
- Tommy Hanson (1986–2015), MLB starting pitcher, primarily with Atlanta Braves
- Chris Harris Jr. (born 1989), cornerback for Denver Broncos
- Mickey Hatcher (born 1955), OU baseball, outfielder for Los Angeles Dodgers and Minnesota Twins
- Andrew Heaney (born 1991), relief pitcher for Los Angeles Angels
- Ryan Helsley (born 1994), relief pitcher for St. Louis Cardinals
- Johny Hendricks (born 1983), former UFC Welterweight Champion, two-time NCAA Wrestling champion
- Josiah Henson (1922–2012), Olympic bronze medalist in freestyle wrestling
- Rusty Hilger (1962–2019), OSU and NFL quarterback
- A. J. Hinch (born 1974), MLB catcher, manager of the Houston Astros
- Danny Hodge (1932–2020), three-time NCAA champion and Olympic silver medalist wrestler
- Mat Hoffman (born 1972), world champion BMX biker
- Matt Holliday (born 1980), designated hitter for the New York Yankees
- Henry Iba (1904–1993), OSU NCAA champion and Olympic champion basketball coach, Basketball Hall of Fame member
- Gabe Ikard (born 1990), center for Buffalo Bills
- Darnell Jackson (born 1985), forward for Sacramento Kings
- Betty Jameson (1919–2009), golfer in World Golf Hall of Fame
- Charlie Johnson (born 1984), guard for Minnesota Vikings
- Felix Jones (born 1987), running back for Dallas Cowboys
- Bob Kalsu (1945–1970), Oklahoma Sooners football and Buffalo Bills player, only active professional football player killed in Vietnam War
- Deji Karim (born 1986), running back for Jacksonville Jaguars
- Matt Kemp (born 1984), MLB outfielder
- Dallas Keuchel (born 1988), pitcher for Atlanta Braves
- Stacey King (born 1967), three-time NBA champion with Chicago Bulls (1991–1993)
- Jon Kolb (born 1947), football player, Oklahoma State and Pittsburgh Steelers center
- Hal Lahar (1919–2003), pro football player, college coach
- Steve Largent (born 1954), Seattle Seahawks wide receiver, Pro Football Hall of Famer and politician
- Abe Lemons (1922–2002), Oklahoma City University, Pan American University, and Texas Longhorns basketball coach
- Frank Lewis (1912–1998), Olympic gold medalist in freestyle wrestling
- Ronnell Lewis (born 1990), NFL player for Detroit Lions
- Joe Lillard (1905–1978), running back for Chicago Cardinals
- Ray Mallouf (1918–2008), NFL quarterback and punter for Chicago Cardinals and New York Giants
- Mickey Mantle (1931–1995), New York Yankees outfielder, Baseball Hall of Famer
- Pepper Martin (1904–1965), St. Louis Cardinals baseball player
- Bryan McCann (born 1987), cornerback for Oakland Raiders
- Gerald McCoy (born 1988), defensive tackle for Tampa Bay Buccaneers
- "Jumping Jack" McCracken (1911–1958), Basketball Hall of Famer
- Tyrus McGee (born 1991), basketball player in the Israel Basketball Premier League
- Leroy McGuirk (1910–1988), professional wrestler and promoter
- Mike McGuirk (born 1958), ring announcer for World Wrestling Federation
- R. W. McQuarters (born 1976), NFL cornerback
- Robert Meachem (born 1984), wide receiver for San Diego Chargers
- Jordy Mercer (born 1986), shortstop for Pittsburgh Pirates
- Shannon Miller (born 1977), Olympic gold medal gymnast
- Garrett Mills (born 1983), tight end for Philadelphia Eagles
- Ryan Minor (born 1974), OU baseball and basketball player
- Kenny Monday (born 1961), Olympic gold and silver medalist in freestyle wrestling
- Gil Morgan (born 1946), professional golfer
- Marty Mornhinweg (born 1962), offensive coordinator for Philadelphia Eagles
- Tommy Morrison (1969–2013), heavyweight champion boxer
- Bobby Murcer (1946–2008), professional baseball player and sportscaster
;N–R
- Rico Noel (born 1989), outfielder for New York Yankees
- Lance Norick (born 1968), NASCAR driver
- Daniel Orton (born 1990), center for Orlando Magic
- Bill Owen (1903–1975), NFL offensive tackle
- Steve Owen (1898–1964), Hall of Fame NFL player and head coach
- Steve Owens (born 1947), OU football player, 1969 Heisman Trophy winner
- Robert Pearce (1908–1996), Olympic gold medalist in freestyle wrestling
- Brad Penny (born 1978), MLB pitcher
- Beth Phoenix (born 1980), professional wrestler
- Darrell Porter (1952–2002), MLB baseball player for St. Louis Cardinals
- Maurkice Pouncey (born 1989), center for Pittsburgh Steelers
- Mike Pouncey (born 1989), center and guard for Miami Dolphins
- Mark Price (born 1964), basketball player; Enid H.S., Georgia Tech, and Cleveland Cavaliers
- J. T. Realmuto (born 1991), MLB player for the Philadelphia Phillies
- Bryant Reeves (born 1973), basketball player, played for Oklahoma State and NBA's Vancouver Grizzlies
- Allie Reynolds (1917–1994), pitcher, Baseball Hall of Famer
- Crystal Robinson (born 1974), New York Liberty, WNBA basketball player
- Bullet Rogan (1893–1967), Baseball Hall of Famer
- Matt Roney (born 1980), MLB relief pitcher
- Jim Ross (born 1952), WWE announcer
- Darrell Royal (1924–2012), football coach at Texas, College Football Hall of Fame
- T. J. Rushing (born 1983), cornerback and return specialist for Detroit Lions
- John Russell (born 1961), bench coach for Baltimore Orioles
- Rex Ryan (born 1962), head coach for Buffalo Bills, New York Jets
- Rob Ryan (born 1962), NFL defensive coordinator
;S–Z
- Barry Sanders (born 1968), running back, OSU Heisman Trophy winner, Pro Football Hall of Famer
- Spec Sanders (1919–2003), football player for New York Yankees (AAFC) and New York Yanks
- Bill Self (born 1962), basketball coach at University of Kansas
- Lee Roy Selmon (1954–2011), OU and NFL player, Pro Football Hall of Fame
- Sterling Shepard (born 1993), wide receiver for the New York Giants
- Jeremy Shockey (born 1980), tight end for New Orleans Saints
- Billy Sims (born 1955), running back OU and Detroit Lions, Heisman Trophy winner
- Antonio Smith (born 1981), defensive end for Denver Broncos
- John Smith (born 1965), two-time NCAA champion at OSU, four-time World and two-time Olympic gold medalist, NCAA and Olympic wrestling coach, Distinguished Member of National Wrestling Hall of Fame
- Pat Smith (born 1970), younger brother of John Smith, first ever four-time NCAA Wrestling Division I Champion
- Reggie Smith (born 1986), safety for Carolina Panthers
- Warren Spahn (1921–2003), pitcher, Baseball Hall of Famer
- Willie Stargell (1940–2001), outfielder, Baseball Hall of Famer with Pittsburgh Pirates
- John Starks (born 1965), basketball player for New York Knicks
- Cory Sullivan (born 1979), outfielder for Houston Astros
- Eddie Sutton (1936–2020), Arkansas and OSU basketball coach
- Jack Swagger (born 1982), OU and WWE professional wrestler
- Barry Switzer (born 1937), football coach, OU and Dallas Cowboys
- Brian Tallet (born 1977), relief pitcher for St. Louis Cardinals
- Ralph Terry (born 1936), pitcher, primarily with New York Yankees
- Jim Thorpe (1887–1953), athlete, Olympic gold medalist, played professional football and Major League Baseball; born in Prague, Oklahoma
- Spencer Tillman (born 1964), All-American running back for OU, TV analyst
- Wayman Tisdale (1964–2009), professional basketball player and jazz musician
- Bob Tway (born 1959), professional golfer, 1986 PGA Championship winner
- Kevin Tway (born 1988), professional golfer
- Ekpe Udoh (born 1987), player for Milwaukee Bucks
- Jack van Bebber (1907–1986), Olympic gold medalist in freestyle wrestling
- J. D. Walton (born 1987), center for New York Giants
- Lloyd "Little Poison" Waner (1906–1982), Baseball Hall of Famer
- Paul "Big Poison" Waner (1903–1965), Baseball Hall of Famer
- "Cowboy" Bill Watts (born 1939), professional wrestler and promoter
- J.C. Watts (born 1957), OU quarterback and U.S. congressman
- Brandon Weeden (born 1983), quarterback for Houston Texans
- Wes Welker (born 1981), wide receiver for Denver Broncos
- Wayne Wells (born 1946), Olympic gold medalist and World champion in freestyle wrestling, first ever Nike signature athlete
- Jason White (born 1980), OU quarterback, Heisman Trophy winner
- Bud Wilkinson (1916–1994), OU coach, College Football Hall of Fame
- Shelby Wilson (born 1937), Olympic gold medalist in freestyle wrestling
- Shelden Williams (born 1983), former NBA player
- Eli Willits (born 2007), shortstop, first overall 2025 draft pick of the Washington Nationals
- Reggie Willits (born 1981), left fielder for the Los Angeles Angels
- Matt Wiman (born 1983), UFC fighter
- James Winchester (born 1989), long snapper for Kansas City Chiefs
- Jamey Wright (born 1974), MLB relief pitcher
- Kenyatta Wright (born 1978), NFL linebacker from Vian, Oklahoma
- Trae Young (born 1998), NBA All-Star point guard for the Atlanta Hawks
Authors
- William Bernhardt (born 1960), novelist
- John Berryman (1914–1972), poet
- Cleora Butler (1901–1985), chef, caterer and cookbook writer
- Ralph Ellison (1914–1994), writer and scholar
- Martin Gardner (1914–2010), author specializing in recreational mathematics
- Tony Hillerman (1925–2008), journalist, historian, professor, and novelist
- S.E. Hinton (born 1948), author and novelist
- Nicole Jordan (born 1954), author
- Oliver LaGrone (1906–1995), sculptor, poet, educator and humanitarian
- Louis L'Amour (1908–1988), western novelist
- Billie Letts (1938–2014), novelist
- Tracy Letts (born 1965), playwright, screenwriter, actor
- N. Scott Momaday (born 1964), author, printmaker
- Bill Moyers (1934–2025), journalist and public commentator
- Jason Nelson (born 1970), internet artist and digital poet
- Wilson Rawls (1913–1984), author
- Jeff Rowland (born 1974), cartoonist, author of WIGU
- Josh Shipp (born 1981), author and motivational speaker
- Jim Thompson (1906–1977), novelist
Aviators and astronauts
- Thomas and Paul Braniff, airline entrepreneurs, founders of Braniff International Airways
- Gordon Cooper (1927–2006), astronaut
- Owen K. Garriott (1930–2019), astronaut
- John Herrington (Chickasaw, born 1958), astronaut
- James Jabara (1923–1966), world's first jet ace, and Korean War triple ace with 15 kills
- Shannon Lucid (born 1943), astronaut
- William R. Pogue (1930–2014), astronaut
- Wiley Post (1898–1935), first pilot to fly solo around the world (born in Texas but grew up in Oklahoma)
- Will Rogers (Cherokee, 1879–1935), aviator
- Thomas Stafford (1930–2024), astronaut
- Clarence L. Tinker (Osage, 1887–1942), U.S. Army Air Corps general and supreme commander of the U.S. Army Air Corps in the Pacific during World War II
Businesspeople
- Rick Bayless (born 1953), restaurateur, chef, PBS television personality
- Clay Bennett (born 1959), chairman, Dorchester Capital; owner, Oklahoma City Thunder
- Sherman Billingsley (1896–1966), owner of Stork Club
- James A. Chapman (1881–1966), oil industry businessman
- Edward K. Gaylord (1873–1974), founder, Daily Oklahoman
- Edward L. Gaylord (1919–2003), editor, Daily Oklahoman; founder, TNN & CMT; owner, Grand Ole Opry
- Sylvan Goldman (1898–1984), businessman and inventor of the shopping cart
- David Green (born 1941), businessman, philanthropist, founder of Hobby Lobby
- J. M. Hall (1851–1935), merchant and pioneer of Tulsa, Oklahoma
- George Kaiser (born 1942), chairman of BOK Financial Corporation
- W. W. Keeler (Cherokee, 1908–1987), principal Chief of Cherokee Nation, president and CEO of Phillips Petroleum Company (1968–1973)
- Henry Kravis (born 1944), co-founder of Kohlberg Kravis Roberts & Co.
- Eugene Lorton (1868–1949), owner, publisher and editor of Tulsa World
- James H. McBirney (1870–1944), founder and president, National Bank of Commerce
- Sam P. McBirney (1877–1936), founder and vice president, National Bank of Commerce, Tulsa
- Cattle Annie (1882–1978), female bandit of the American Old West
- Little Britches (born 1879; year of death unknown), female bandit, companion in crime with Cattle Annie
- Quanah Parker (Comanche, c. late 1840s–1911), chief and co-founder of the Native American Church
- Peter Pitchlynn (Choctaw, 1806–1881), provisional Choctaw chief, Choctaw delegate to Washington, D.C.; buried in the Congressional Cemetery
- Pleasant Porter (Muscogee, 1840–1907), Muscogee (Creek) Nation principal chief
- Harvey Pratt (Southern Cheyenne, 1941–2025), Native American forensic artist, Cheyenne peace chief
- Will Rogers (Cherokee, 1879–1935), humorist, actor, author, aviator, movie producer
- John Ross (Cherokee, 1790–1866), principal chief of the Cherokee Nation, buried at Park Hill, Oklahoma
- Steve Russell (born 1947), Cherokee, poet, academic (emeritus professor), journalist and trial judge
- Sequoyah (Cherokee, 1776–1842), lived in what is now Sequoyah County; blacksmith, teacher, inventor of the Cherokee syllabary
- Maria Tallchief (Osage Nation, 1925–2013), first American prima ballerina
- Marjorie Tallchief (Osage Nation, 1926–2021), ballerina
- Clarence L. Tinker (Osage Nation, 1887–1942), U.S. Army Air Corps general, first American general to die in World War II
- Fred Waite (Chickasaw, 1853–1895), cowboy, member of Billy the Kid's gang and politician
- Della Warrior (Otoe-Missouria, born 1946), first female chairperson of the Otoe-Missouria Tribe of Indians, president of the Institute of American Indian Arts, executive director of the Museum of Indian Arts and Culture
- Stand Watie (Cherokee, 1806–1871), brigadier general in the Confederate Army, chief
Radio and television personalities
- Rick Bayless (born 1953), chef and television personality
- Skip Bayless (born 1951), sports journalist
- Douglas Edwards (1917–1990), radio and television journalist
- Gary England (born 1939), chief meteorologist for KWTV Channel 9
- Kathy Lee Gifford (born 1953), television personality, Oral Roberts graduate
- Kayne Gillaspie (born 1979), television personality and fashion designer
- Mary Hart (born 1950), television personality, co-host of Entertainment Tonight
- Paul Harvey (1918–2009), radio broadcaster and commentator
- Glenn Hauser (born 1945), radio broadcaster
- Phil McGraw (born 1950), television psychologist
- Bill Moyers (born 1934), television journalist
- Bob Murphy (1924–2004), sportscaster, play-by-play for New York Mets
- Ross Porter (born 1938), longtime broadcaster for Los Angeles Dodgers
- Dan Rowan (1922–1987), comedian, Rowan & Martin's Laugh-In
- Judy Woodruff (born 1946), television journalist
Scientists, including medicine
- Richard E. Berendzen (born 1938), astronomer, author, and professor
- Kenneth H. Cooper (born 1931), physician, United States Air Force officer, pioneer of aerobics
- David Deming (born 1954), PhD, author, professor of geology, and political commentator
- Edwin R. Gilliland (1909–1973), chemical engineer and professor
- Lyle Goodhue (1903–1981), research chemist and inventor
- Karl Guthe Jansky (1905–1950), physicist and radio engineer
- Dr. Donna J. Nelson (born 1954), OU chemistry professor, 2016 ACS president, and science advisor to Breaking Bad
- Dr. Reed Timmer (born 1980), extreme meteorologist, storm chaser
- John York (born 1949), cancer research pathologist
Religious figures
- Wade Burleson (born 1961), lead pastor of Emmanuel Enid (1992–present) and president of the Baptist General Convention of Oklahoma (2002–2004)
- Finis Alonzo Crutchfield (1916–1987), Methodist minister and Bishop of Oklahoma
- Paul Vernon Galloway (1904–1990), Methodist minister and Bishop of Texas, Arkansas and Louisiana
- Jerry Johnston (born 1959), Southern Baptist clergyman and university administrator, born in Oklahoma City
- Charles William Kerr (1875–1951), first permanent Protestant minister in Tulsa, Oklahoma
- Robert McGill Loughridge (1809–1900), Presbyterian missionary
- Quanah Parker (Comanche, 1852–1911), Native American Church leader and advocate
- Oral Roberts (1918–2009), evangelist
- Stanley Rother (1935–1981), first U.S.-born priest and martyr to be beatified by Roman Catholic church
- John Wilson (Caddo) (ca. 1840–1901), Native American Church roadman
- Yahweh ben Yahweh (born Hulon Mitchell Jr.) (1935–2007), leader of religious group Nation of Yahweh
Visual artists
- Joe Andoe (born 1955), painter
- Fred Beaver (Seminole/Muscogee, 1911–1980), painter, printmaker
- Charles Bell (1935–1995), photorealist painter
- Acee Blue Eagle (Muscogee, 1907–1959), artist
- Carolyn Brady (1937–2005), artist
- Joe Brainard (1942–1994), artist
- T.C. Cannon (Kiowa/Caddo, 1946–1978), artist
- Larry Clark (born 1943), photographer, filmmaker
- Woody Crumbo (Citizen Potawatomi, 1912–1989), artist
- Joseph Glasco (1925–1996), abstract expressionist artist
- Joe Goode (born 1937), artist
- Chester Gould (1900–1985), creator of the Dick Tracy comic strip
- Stephen Hillenburg (1961–2018), cartoonist, creator of SpongeBob SquarePants
- Allan Houser (Chiricahua Apache, 1914–1994), sculptor
- Robert McMurtry (1950–2012), painter, author
- Jason Nelson (born 1970), internet artist and digital poet
- Gary Panter (born 1950), illustrator, painter and designer
- Joe A. Rector (1935–2012), artist
- Ed Ruscha (born 1937), artist
- David Salle (born 1952), artist
- Leon Polk Smith (European-American, 1906–1996), artist
- Willard Stone (1916–1985), sculptor and woocdarver
Other
- Bobby Baldwin (born c. 1950), professional poker player
- Daniel J. Boorstin (1914–2004), historian, professor, attorney, and writer
- Tom Colbert (born 1949), first African-American Oklahoma Supreme Court justice
- Kim Davenport (born 1955), professional pool player
- David Duke (born 1950), white nationalist, politician, antisemitic conspiracy theorist
- Ben Graf Henneke (1914–1999), educator; president, University of Tulsa
- Anita Hill (born 1956), professor of social policy, law, and women's studies who testified at the U.S. Senate confirmation hearings of Clarence Thomas
- Sherri Hill (born 1949), fashion designer; grew up in Minco
- Ray William Johnson (born 1981), Internet comedian and musician
- Stephen Jones (born 1940), attorney; Timothy McVeigh's lead defense lawyer during McVeigh's trial for the Oklahoma City bombing
- Robert L. Lynn (1931–2020), college administrator and president, journalist and poet; reared in Carter County
- Charles ("Chuck") W. Mooney Jr. (born 1947), the Charles A. Heimbold Jr. Professor of Law, and former interim dean, at the University of Pennsylvania Law School
- Charles Page (1860–1920), philanthropist and founder of Sand Springs, Oklahoma
- Joe Redington (1917–1999), "Father of the Iditarod Trail Sled Dog Race"
- Bass Reeves (1838–1910), first African-American U.S. marshal and one of the chief law enforcement agents in early Oklahoma
- Kevin Samuels (born 1966), YouTuber
- Steven W. Taylor (born 1949), Oklahoma Supreme Court justice, presided over Oklahoma City bombing suspect Terry Nichols's state murder trial
- Cornel West (born 1953), scholar
- Kathleen Zellner, attorney
See also
- List of Oklahoma suffragists
- List of Northeastern State University alumni
- List of Oklahoma State University people
- List of people from Enid, Oklahoma
- List of people from Muskogee, Oklahoma
- List of people from Norman, Oklahoma
- List of people from Oklahoma City
- List of people from Tulsa, Oklahoma
- List of University of Central Oklahoma people
- List of University of Oklahoma people
- List of University of Tulsa people
- Lists of Americans
