{|class="wikitable sortable"
|-
! Senator !! Lifespan !! Party !! Prov. !! Entered !! Left !! Appointed by !! Left due to !! For life?
|-
| Nicole Eaton || 1945–present || C || ON || 2 January 2009 || 21 January 2020 || Harper || Retirement ||
|-
| William Cameron Edwards || 1844–1921 || L || ON || 17 March 1903 || 17 September 1921 || Laurier || Death || Y
|-
| Art Eggleton || 1943–present || L || ON || 24 March 2005 || 29 September 2018 || Martin || Retirement ||
|-
| John Campbell Elliott || 1872–1941 || L || ON || 29 January 1940 || 20 December 1941 || King || Death || Y
|-
| John Valentine Ellis || 1835–1913 || L || NB || 3 September 1900 || 10 June 1913 || Laurier || Death || Y
|-
| Clarence Emerson || 1901–1963 || PC || NB || 12 October 1957 || 25 September 1963 || Diefenbaker || Death || Y
|-
| Henry Read Emmerson || 1883–1954 || L || NB || 25 June 1949 || 21 June 1954 || St. Laurent || Death || Y
|-
| Tobias Enverga || 1955–2017 || C || ON || 6 September 2012 || 16 November 2017 || Harper || Death ||
|-
| Raymond Eudes || 1912–1980 || L || QC || 8 April 1968 || 25 October 1980 || Pearson || Death ||
|-
| William Daum Euler || 1875–1961 || L || ON || 11 May 1940 || 15 July 1961 || King || Death || Y
|-
| Douglas Everett || 1927–2018 || L || MB || 8 November 1966 || 20 January 1994 || Pearson || Resignation ||
|-
| John Ewasew || 1922–1978 || L || QC || 17 December 1976 || 26 March 1978 || Trudeau, P. || Death ||
|-
| Trevor Eyton || 1934–2019 || C || ON || 23 September 1990 || 12 July 2009 || Mulroney || Retirement ||
|}