{|class="wikitable sortable"
|-
! Senator !! Lifespan !! Party !! Prov. !! Entered !! data-sort-type="date" | Left !! Appointed by !! Left due to !! For life?
|-
| Jean-Guy Dagenais || 1950–present|| C || QC || 17 January 2012 || — || Harper || — ||
|-
| Armand Daigle || 1892–1957 || L || QC || 3 March 1944 || 8 March 1957 || King || Death || Y
|-
| Roméo Dallaire || 1946–present|| L || QC || 24 March 2005 || 17 June 2014 || Martin || Resignation ||
|-
| Pierre Dalphond || 1954–present|| || QC || 6 June 2018 || — || Trudeau, J. || — ||
|-
| Raoul Dandurand || 1861–1942 || L || QC || 22 January 1898 || 11 March 1942 || Laurier || Death || Y
|-
| John Waterhouse Daniel || 1845–1933 || C || NB || 18 March 1912 || 11 January 1933 || Borden || Death || Y
|-
| Donna Dasko || 1951–present|| || ON || 6 June 2018 || — || Trudeau, J. || — ||
|-
| Keith Davey || 1926–2011 || L || ON || 24 February 1966 || 1 July 1996 || Pearson || Resignation ||
|-
| Athanase David || 1882–1953 || L || QC || 9 February 1940 || 26 January 1953 || King || Death || Y
|-
| Laurent-Olivier David || 1840–1926 || L || QC || 19 June 1903 || 24 August 1926 || Laurier || Death || Y
|-
| Paul David || 1919–1999 || PC || QC || 16 April 1985 || 25 December 1994 || Mulroney || Retirement ||
|-
| Rupert Davies || 1879–1967 || L || ON || 19 November 1942 || 11 March 1967 || King || Death || Y
|-
| John Caswell Davis || 1888–1953 || L || MB || 25 January 1949 || 25 October 1953 || St. Laurent || Death || Y
|-
| Thomas Osborne Davis || 1856–1917 || L || NT<br>SK || 30 September 1904<br>1 September 1905 || 1 September 1905<br>23 January 1917 || Laurier || Death || Y
|-
| Dennis Dawson || 1949–present|| L || QC || 2 August 2005 || 8 February 2023 || Martin || Resignation ||
|-
| Joseph A. Day || 1945–2024 || L || NB || 4 October 2001 || 24 January 2020 || Chrétien || Retirement ||
|-
| Pierre de Bané || 1938–2019 || L || QC || 29 June 1984 || 2 August 2013 || Trudeau, P. || Retirement ||
|-
| Robert de Cotret || 1944–1999 || PC || ON || 5 June 1979 || 14 January 1980 || Clark || Resignation ||
|-
| Colin Deacon || 1959–present|| || NS || 15 June 2018 || — || Trudeau, J. || — ||
|-
| Marty Deacon || 1958–present|| || ON || 15 February 2018 || — || Trudeau, J. || — ||
|-
| Tony Dean || 1953–present|| NA || ON || 10 November 2016 || — || Trudeau, J. || — ||
|-
| Pierre Antoine Deblois || 1815–1898 || C || QC || 13 February 1883 || 21 June 1898 || Macdonald || Death || Y
|-
| Alphonse-Arthur Miville Déchêne || 1848–1902 || L || QC || 13 May 1901 || 1 May 1902 || Laurier || Death || Y
|-
| Jacques Demers || 1944–present|| C→NA || QC || 27 August 2009 || 25 August 2019 || Harper || Retirement ||
|-
| Azellus Denis || 1907–1991 || L || QC || 3 February 1964 || 4 September 1991 || Pearson || Death || Y
|-
| William Dennis || 1856–1920 || IC || NS || 20 November 1912 || 11 July 1920 || Borden || Death || Y
|-
| William Henry Dennis || 1887–1954 || C || NS || 3 February 1932 || 18 January 1954 || Bennett || Death || Y
|-
| Daniel Derbyshire || 1846–1916 || L || ON || 22 November 1907 || 18 June 1916 || Laurier || Death || Y
|-
| Jean-Paul Deschatelets || 1912–1986 || L || QC || 24 February 1966 || 10 January 1986 || Pearson || Resignation ||
|-
| Alphonse Desjardins || 1841–1912 || C || QC || 1 October 1892 || 16 June 1896 || Abbott || Resignation || Y
|-
| Jean Noël Desmarais || 1924–1995 || PC || ON || 4 June 1993 || 25 July 1995 || Mulroney || Death ||
|-
| Paul Desruisseaux || 1905–1982 || L || QC || 8 July 1966 || 1 May 1980 || Pearson || Retirement ||
|-
| Georges-Casimir Dessaulles || 1827–1930 || L || QC || 12 March 1907 || 19 April 1930 || Laurier || Death || Y
|-
| Jean-Marie Dessureault || 1888–1970 || L || QC || 9 June 1945 || 16 August 1970 || King || Resignation || Y
|-
| Leverett George DeVeber || 1849–1925 || L || AB || 8 March 1906 || 9 July 1925 || Laurier || Death || Y
|-
| James Dever || 1825–1904 || L || NB || 14 March 1868 || 7 May 1904 || Macdonald || Death || Y
|-
| Mabel DeWare || 1926–2022|| PC || NB || 23 September 1990 || 9 August 2001 || Mulroney || Retirement ||
|-
| Consiglio Di Nino || 1938–present|| C || ON || 30 August 1990 || 30 June 2012 || Mulroney || Retirement ||
|-
| Robert B. Dickey || 1812–1903 || C || NS || 23 October 1867 || 14 July 1903 || Royal proclamation || Death || Y
|-
| Fred Dickson || 1937–2012 || C || NS || 22 December 2008 || 9 February 2012 || Harper || Death ||
|-
| Walter Hamilton Dickson || 1806–1885 || C || ON || 23 October 1867 || 19 February 1884 || Royal proclamation || Resignation || Y
|-
| John Dobson || 1824–1907 || C || ON || 23 February 1892 || 27 January 1907 || Abbott || Death || Y
|-
| James Domville || 1842–1921 || L || NB || 20 April 1903 || 30 July 1921 || Laurier || Death || Y
|-
| Richard Donahoe || 1909–2000 || PC || NS || 13 September 1979 || 27 September 1984 || Clark || Retirement ||
|-
| James J. Donnelly || 1866–1948 || C || ON || 26 May 1913 || 20 October 1948 || Borden || Death || Y
|-
| C. William Doody || 1931–2005 || C || NL || 3 October 1979 || 27 December 2005 || Clark || Death ||
|-
| James Joseph Hayes Doone || 1888–1953 || L || NB || 25 June 1949 || 6 April 1953 || St. Laurent || Death || Y
|-
| James Moffat Douglas || 1839–1920 || IL || SK || 8 March 1906 || 19 August 1920 || Laurier || Death || Y
|-
| Percy Downe || 1954–present|| L || PE || 26 June 2003 || — || Chrétien || — ||
|-
| Norman Doyle || 1945–present|| C || NL || 6 January 2012 || 11 November 2020 || Harper || Retirement ||
|-
| Richard Doyle || 1923–2003 || PC || ON || 19 March 1985 || 10 March 1998 || Mulroney || Retirement ||
|-
| Mark Robert Drouin || 1903–1963 || PC || QC || 4 October 1957 || 12 October 1963 || Diefenbaker || Death || Y
|-
| George Alexander Drummond || 1829–1910 || C || QC || 1 December 1888 || 2 February 1910 || Macdonald || Death || Y
|-
| Pamphile Réal Du Tremblay || 1879–1955 || L || QC || 19 November 1942 || 6 October 1955 || King || Death || Y
|-
| Antoine Juchereau Duchesnay || 1809–1886 || C || QC || 23 October 1867 || 7 January 1871 || Royal proclamation || Resignation || Y
|-
| Elzéar-Henri Juchereau Duchesnay || 1809–1871 || C || QC || 23 October 1867 || 12 May 1871 || Royal proclamation || Death || Y
|-
| William Duff || 1872–1953 || L || NS || 28 February 1936 || 25 April 1953 || King || Death || Y
|-
| Joseph James Duffus || 1876–1957 || L || ON || 15 February 1940 || 7 February 1957 || King || Death || Y
|-
| Mike Duffy || 1946–present|| C→NA || PE || 2 January 2009 || 27 May 2021 || Harper || Retirement ||
|-
| James Duggan || 1903–1980 || L || NL || 8 July 1966 || 28 February 1978 || Pearson || Resignation ||
|-
| Ron Duhamel || 1938–2002 || L || MB || 15 January 2002 || 30 September 2002 || Chrétien || Death ||
|-
| Léandre Dumouchel || 1811–1882 || C || QC || 23 October 1867 || 23 September 1882 || Royal proclamation || Death || Y
|-
| Pat Duncan || 1960–present|| || YT || 12 December 2018 || — || Trudeau, J. || — ||
|-
| Suzanne Duplessis || 1940–present|| C || QC || 22 December 2008 || 30 June 2015 || Harper || Retirement ||
|-
| Renée Dupuis || 1949–present|| NA || QC || 10 November 2016 || 16 January 2024 || Trudeau, J. || Retirement ||
|-
| Vincent Dupuis || 1889–1967 || L || QC || 18 April 1945 || 11 May 1967 || King || Death || Y
|-
| Lillian Dyck || 1945–present|| IND→IL→L || SK || 24 March 2005 || 24 August 2020 || Martin || Retirement ||
|}