Many fungi and microorganisms have been domesticated by humans for use in food production, medicine, and research. The following is a list of domesticated fungi and microorganisms:

Food

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! Organism !! Use

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| Agaricus bisporus || Eaten; "Button mushroom" or "portabello mushroom".

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| Aspergillus oryzae || Fermentation of traditional Japanese foods and beverages.

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| bacteria || (for cheese, yogurt, kephir, buttermilk, sour cream, kombucha tea, spirulina)

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| Lactic acid bacteria || Fermentation of dairy, plants, and meats.

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| Lactobacillus delbrueckii || Production of yogurt (Bulgaria).

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| Streptococcus thermophilus || Production of yogurt (France, United Kingdom).