Listed in order going downstream:
- British Columbia:
- Headwaters to the Canada–United States border:
- Canal Flats
- Fairmont Hot Springs
- Windermere
- Invermere
- Radium Hot Springs
- Spillimacheen
- Golden
- Mica Creek
- Revelstoke
- Nakusp
- Castlegar
- Trail
- Washington:
- Canada–United States border to Grand Coulee Dam:
- Northport
- Kettle Falls
- Inchelium
- Grand Coulee
- Coulee Dam
- Grand Coulee Dam to Wenatchee:
- Elmer City
- Bridgeport
- Brewster
- Pateros
- Entiat
- West Wenatchee
- Wenatchee
- East Wenatchee
- South Wenatchee
- South Wenatchee to Wallula:
- Rock Island
- Vantage
- Desert Aire
- Richland
- Kennewick
- Pasco
- Burbank
- Wallula
- Washington-Oregon border:
- Umatilla to The Dalles:
- Umatilla, Oregon
- Irrigon, Oregon
- Boardman, Oregon
- Roosevelt, Washington
- Arlington, Oregon
- Rufus, Oregon
- Maryhill, Washington
- Biggs Junction, Oregon
- Wishram, Washington
- Dallesport, Washington
- The Dalles, Oregon
- The Dalles to Portland:
- Lyle, Washington
- Rowena, Oregon
- Mosier, Oregon
- Bingen, Washington
- White Salmon, Washington
- Hood River, Oregon
- Carson River Valley, Washington
- Stevenson, Washington
- Cascade Locks, Oregon
- North Bonneville, Washington
- Washougal, Washington
- Camas, Washington
- Vancouver, Washington
- Portland to the mouth of the Columbia:
- Portland, Oregon
- St. Helens, Oregon
- Columbia City, Oregon
- Kalama, Washington
- Goble, Oregon
- Prescott, Oregon
- Rainier, Oregon
- Longview, Washington
- Cathlamet, Washington
- Astoria, Oregon
- Warrenton, Oregon
- Chinook, Washington
- Ilwaco, Washington
See also
- Columbia River
- Tributaries of the Columbia River
- Hydroelectric dams on the Columbia River