As of May 2021, Iberia flies to 26 domestic and 64 international destinations across Africa, the Americas, Asia and Europe. This list does not include irregular charters and destinations served by Air Nostrum operating as Iberia Regional or Iberia Express.
List
{|class="sortable wikitable"
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!Country
!City
!Airport
!Notes
!Refs
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|Albania||Tirana||Tirana International Airport Nënë Tereza||||align=center|
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|rowspan="2"|Algeria||Algiers||Houari Boumediene Airport||align=center| ||align=center|
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|rowspan="2"|Argentina||Buenos Aires||Ministro Pistarini International Airport||align=center| ||align=center|
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|Salzburg||Salzburg Airport||align=center| ||align=center|
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|Vienna||Vienna International Airport||align=center| ||align=center|
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|Rio de Janeiro||Rio de Janeiro/Galeão International Airport||align=center| ||align=center|
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|Chile||Santiago||Arturo Merino Benítez International Airport||align=center| ||align=center|
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|Medellín||José María Córdova International Airport||align=center| ||align=center|
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|Czech Republic||Prague||Václav Havel Airport Prague||align=center| ||align=center|
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|Dominican Republic||Santo Domingo||Las Américas International Airport||align=center| ||align=center|
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|rowspan="2"|Ecuador||Guayaquil||José Joaquín de Olmedo International Airport||align=center| ||align=center|
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|Quito||Mariscal Sucre International Airport||align=center| ||align=center|
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|El Salvador||San Salvador||El Salvador International Airport||align=center| ||align=center|
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|rowspan="3"|France||Marseille||Marseille Provence Airport||align=center| ||align=center|
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|Gibraltar||Gibraltar||Gibraltar International Airport||||align=center|
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|Greece||Athens||Athens International Airport||align=center| ||align=center|
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|India||Mumbai||Chhatrapati Shivaji Maharaj International Airport||align=center| ||align=center|
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|Iran||Tehran||Mehrabad International Airport||||align=center|
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|Catania||Catania–Fontanarossa Airport||||align=center|
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|rowspan="2"|Milan||Milan Linate Airport||align=center| ||align=center|
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|Palermo||Falcone Borsellino Airport||||align=center|
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|Kuwait||Kuwait City||Kuwait International Airport||||align=center|
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|Mauritania||Nouakchott||Nouakchott International Airport||||align=center|
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|Mexico||Mexico City||Mexico City International Airport||align=center| ||align=center|
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|Marrakesh||Marrakesh Menara Airport||align=center| ||align=center|
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|rowspan="3"|Norway||Bergen||Bergen Airport, Flesland||||align=center|
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|Oslo||Oslo Airport, Gardermoen||align=center| ||align=center|
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|Tromsø||Tromsø Airport||||align=center|
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|Panama||Panama City||Tocumen International Airport||align=center| ||align=center|
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|Romania||Bucharest||Bucharest Henri Coandă International Airport||||align=center|
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|rowspan="2"|Russia||Moscow||Moscow Domodedovo Airport||||align=center|
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|Slovenia||Ljubljana||Ljubljana Jože Pučnik Airport||align=center| ||align=center|
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|Senegal||Dakar||Blaise Diagne International Airport||align=center| ||align=center|
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|rowspan="14"|Spain||A Coruña||A Coruña Airport||align=center| ||align=center|
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|Palma de Mallorca||Palma de Mallorca Airport||||align=center|
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|United Kingdom|||London||Heathrow Airport||align=center| ||align=center|
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|Chicago||O'Hare International Airport||align=center| ||align=center|
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|Los Angeles||Los Angeles International Airport||align=center| ||align=center|
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|San Juan||Luis Muñoz Marín International Airport||align=center| ||align=center|
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|Washington, D.C.||Dulles International Airport||||align=center|
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|Uruguay||Montevideo||Carrasco International Airport||align=center| ||align=center|