LES or Les may refer to:

People

  • Les (given name)
  • Les (surname)
  • L.E.S. (producer), hip hop producer

Space flight

  • Launch Entry Suit, worn by Space Shuttle crews
  • Launch escape system, for spacecraft emergencies
  • Lincoln Experimental Satellite series, 1960s and 1970s

Biology and medicine

  • Lazy eye syndrome, or amblyopia, a disorder in the human optic nerve
  • The Liverpool epidemic strain of Pseudomonas aeruginosa
  • Lower esophageal sphincter
  • Lupus erythematosus systemicus

Places

  • The Lower East Side neighborhood of Manhattan, New York City
  • Les, Catalonia, a municipality in Spain
  • Leş, a village in Nojorid Commune, Bihor County, Romania
  • Les, the Hungarian name for Leșu Commune, Bistriţa-Năsăud County, Romania
  • Les, a village in Tejakula district, Buleleng regency, Bali, Indonesia
  • Lesotho, IOC and UNDP country code
  • Lès, a word featuring in many French placenames

Transport

  • Leigh-on-Sea railway station, National Rail station code
  • Leytonstone tube station, London Underground station code

Other uses

  • "L.E.S.", a song by Childish Gambino from Camp (album)
  • Lake-effect snow
  • Large eddy simulation in fluid dynamics
  • Law Enforcement Sensitive, a US security classification
  • Leave and Earnings Statement, of US military
  • Les (Vietnam), a Vietnamese term for lesbians
  • Les+ Magazine, a Chinese LGBT magazine
  • Licensing Executives Society International, a US intellectual property organization
  • Life Extension Society, a cryonics organization
  • Lifetime Entertainment Services, a US company
  • Lilliput Edison screw, a 5mm light bulb socket
  • Louisiana Energy Services, which operates the National Enrichment Facility
  • A Slang term for Lesbian