Labeo is an ancient Roman cognomen derived from the word labea (English: lip), originally referring to a person with thick or prominent lips.

Labeo may refer to:

  • Attius Labeo, 1st century AD Roman writer whose translations of the Iliad and the Odyssey were derided
  • Claudius Labeo, Batavian military leader who fought for Rome in the Batavian rebellion (69–70 AD)
  • Cornelius Labeo, 3rd century AD(?) Roman theologian and antiquarian
  • Gaius Atinius Labeo (praetor 195 BC), tribune of the plebs in 196 BC
  • Gaius Atinius Labeo (praetor 190 BC)
  • Marcus Antistius Labeo (died 10 or 11 AD), Roman jurist, son of Pacuvius Labeo
  • Pacuvius Labeo (died 42 BC), Roman jurist and assassin of Julius Caesar
  • Quintus Fabius Labeo (), Roman quaestor, praetor, consul and pontiff