LPR may refer to:
- Laryngopharyngeal reflux, a form of acid reflux
- Lawful permanent resident
- Lazarus Program file
- Libertarian Party of Russia
- License plate recognition
- Liga Puerto Rico, top division association football league in Puerto Rico
- Line Printer Remote/Daemon protocol (RFC1179)
- League of Polish Families (), a Polish political party
- (League of the Right of the Republic), a Polish political alliance
- Light pollution reduction
- Living Planet Report, a WWF analysis on the health of our planet
- (Le) Poisson Rouge, a music venue in New York City
- ' (Polish Medical Air Rescue), Polish air ambulance service
- Low-power radio
- Long Preston railway station, station code LPR
- LPR (cycling team), a former professional cycling team
- Luhansk People's Republic, a self-proclaimed statelet in eastern Ukraine
- A US Navy hull classification symbol: Amphibious transport, small (LPR)