Knox County is a county located in the northeast portion of the U.S. state of Missouri. As of the 2020 census, its population was 3,744, making it the third-least populous county in Missouri. Its county seat is Edina. The county was organized February 14, 1845, and named for U.S. Secretary of War General Henry Knox.

Civil War

A battle was fought during the American Civil War at Newark, involving Joseph C. Porter on August 1, 1862.

Geography

According to the U.S. Census Bureau, the county has a total area of , of which is land and (0.6%) is water.

Adjacent counties

  • Scotland County (north)
  • Clark County (northeast)
  • Lewis County (east)
  • Shelby County (south)
  • Macon County (southwest)
  • Adair County (west)

Major highways

  • 20px Route 6
  • 20px Route 11
  • 20px Route 15
  • 20px Route 151
  • 20px Route 156

Demographics