Prince Karol Stanisław Radziwiłł () (27 November 1669– 2 August 1719) was a Polish–Lithuanian nobleman and diplomat.
Ordynat of Nieśwież, Stolnik of Lithuania in 1685, Equerry of Lithuania in 1686, Deputy Chancellor of Lithuania in 1690, Grand Chancellor of Lithuania in 1698, Bailiff of Vilnius.
He married Anna Katarzyna Sanguszko on March 6, 1691 in Vilnius. He was awarded the Order of the White Eagle.