Kamehameha may refer to:
House of Kamehameha
- House of Kamehameha, the dynasty of the Hawaiian Kings
- Kamehameha I (1736–1819), first king of the Hawaiian Islands
- Kamehameha II (1797–1824), second king of the Kingdom of Hawaii
- Kamehameha III (1813–1854), King of Hawaii from 1825 to 1854
- Kamehameha IV (1834–1863), fourth king of Hawaii from 1855 to 1863
- Kamehameha V (1830–1872), reigned as monarch of the Kingdom of Hawaiʻi from 1863 to 1872
- Albert Kamehameha (1858–1862), crown prince of Hawaii
- David Kamehameha (1828–1835), member of the royal family of the Kingdom of Hawaii
Other uses
- Kamehameha (Dragon Ball), a fictional technique mainly used by Son Goku, Son Gohan, and Master Roshi in the Dragon Ball franchise
- Kamehameha Highway, one of the main highways in Oʻahu
- Kamehameha Schools, private school system in Hawaiʻi
- Kamehameha Day, public holiday in Hawaii on June 11
- Fort Kamehameha, former United States Army military base
- King Kamehameha (horse) (foaled 2001), Japanese Thoroughbred racehorse and sire
- USS Kamehameha (SSBN-642), Benjamin Franklin-class ballistic missile submarine
- Kamehameha butterfly, a species of butterfly endemic to Hawaii