thumb|right|Juan de Grijalva
Juan de Grijalva (; c. 1490 – 21 January 1527) was a Spanish conquistador, and a relative of Diego Velázquez. He went to Hispaniola in 1508 and to Cuba in 1511. He was one of the early explorers of the Mexican coastline, and was killed by natives in Honduras on 21 January 1527.
1518 expedition
thumb|left|150px|Meeting between Juan de Grijalva and the Mayan chieftain Tabscoob, occurred in Potonchán in 1518.
In 1518, Grijalva became one of the first to explore the shores of Mexico. According to Hernán Cortés, 170 people went with him, but according to Pedro Mártir, there were 300 people.<br>
The main pilot was Antón de Alaminos, the other pilots were Juan Álvarez (also known as el Manquillo), Pedro Camacho de Triana, and Grijalva. Other members included Francisco de Montejo, Pedro de Alvarado, Bernal Díaz del Castillo, Juan Díaz, Francisco Peñalosa, Alonso de Ávila, The Río Grijalva in Mexico was named after him. He was also the first Spaniard to encounter Moctezuma II's delegation. One of the natives joined them, being baptized as Francisco, and became a Nahuatl interpreter on Cortes' expedition. Bernal Díaz del Castillo wrote about the travels of Juan de Grijalva in his book Historia de las Indias..