José Luis López may refer to:
- José Luis López Aranguren, Spanish philosopher, see Prince of Asturias Awards
- José Luis López Rubio or José López Rubio, Spanish film writer and director
- José Luis López Vázquez (1922–2009), Spanish film and TV actor
- José Luis López (Costa Rican footballer), Costa Rican footballer
- José Luis López (Mexican footballer) (born 1979), Mexican footballer
- José Luis López (boxer) (born 1973), Mexican boxer
- José Luis López (handballer) (born 1998), Chilean handball player
See also
- José López (disambiguation)
- Luis Lopez (disambiguation)