thumb|Aerial view of John Rankin Lock and Dam on the Tennessee-Tombigbee Waterway. View is upriver to the north.
The John Rankin Lock (formerly named Lock D) is part of the Tennessee-Tombigbee Waterway (popularly known as the "Tenn-Tom"). It is located in Itawamba County, Mississippi, approximately north of Fulton.
The lock is part of a series of five locks within a stretch of the Tenn-Tom known as the "Chain of lakes" or canal section. The lock has a lift of 30 feet.
Formerly known simply as Lock D, the lock was later renamed for John E. Rankin, a former Mississippi First District Representative in the United States House of Representatives and an early champion of the Tenn-Tom.
