John Patrick Hopkins (October 29, 1858October 13, 1918) was an American politician who served as the 35th mayor of Chicago from 1893 to 1895. A member of the Democratic Party, Hopkins was the first of nine Irish American Catholic mayors of Chicago.

His tenure was marred by numerous scandals, criticisms, and shortcomings. This included incidents of political corruption in the city, such as the Ogden Gas Scandal, rampant public gambling that drew the ire of the Chicago Civic Federation, an indecisive response by Hopkins to the Pullman Strike that was assailed by Republican press outlets. Additionally, the misappropriation of significant amounts of campaign contributions by Hopkins had upset many in the Chicago Democratic party, including those who belonged to the party's former Harrison faction. He is buried in Calvary Cemetery in Evanston, Illinois.