Jan Karol Tarło () was a Polish–Lithuanian noble (szlachcic).
He was the son of starost Stanisław Tarło and Barbara Dulska. He married Marianna Ligęza around 1636.
He was castellan of Wiślice and starost of Olsztyn and Zwoleń.
His daughter Barbara married Jerzy Sebastian Lubomirski, a powerful magnate and hetman.