The James Weir House (also called the Weir-McNeeley House) is a historic building formerly located in downtown Tazewell, Tennessee, United States.
It was built by James Weir around 1830 as a two-story single-pen log structure, It was being restored to its original condition by Verlin Singleton. The restoration was expected to be completed early in 2008, after which the house was to be open to the public by appointment only. The house was removed from the National Register in 2021.