Interstate 76 Business (I-76 Bus) is an unsigned business spur that connects Keenesburg, Colorado, in Weld County to the Interstate. Inventoried by the Colorado Department of Transportation (CDOT), the route begins at the I-76 frontage road (County Road 398) within the town limits and heads north as Market Street. The route terminates north of I-76 exit 39.

Major intersections<br/>