Hot zone may refer to:
- The Hot Zone, a 1994 non-fiction book by Richard Preston
- Hot zone (environment), a location that is considered to be dangerous
Television
- HOT Zone, an Israeli TC channel on the Hot cable service
- Combat Hospital, aka The Hot Zone, a 2011 Canadian TV series
- The Hot Zone (American TV series), 2019 TV series based on the Richard Preston book
- "Hot Zone" (Stargate Atlantis), a season 1 episode of the TV series Stargate Atlantis
Other uses
- Hot Zone, an alternative name for the Transformers character "Hot Spot"
- Hot-zone, a wireless wide area network offering internet access
See also
- War zone (disambiguation)
- Hot (disambiguation)
- Zone (disambiguation)