Hooft or 't Hooft is a Dutch surname meaning "(the) head" (hoofd in modern Dutch). Notable people with the surname include:
;Hooft
- Cornelis Hooft (1547–1627), Dutch statesman, father of P.C. Hooft
- Pieter Corneliszoon Hooft (1581–1647), Dutch historian, poet and playwright
- (1617–1678), Dutch mayor of Amsterdam,
- Catharina Hooft (1618–1691), woman of the Dutch Golden Age
- Hendrik Daniëlsz Hooft (1716–1794), Dutch politician during the Patriottentijd
- Jeannette Hooft (1888–1939), Dutch traveler, mountaineer, and writer
- Henri Hooft (born 1969), Dutch kickboxer and trainer
;'t Hooft / Visser 't Hooft / Van 't Hooft
- Willem Visser 't Hooft (1900–1985), Dutch theologian and the first secretary general of the World Council of Churches
- Haas Visser 't Hooft (1905–1977), Dutch field hockey player
- Francis van 't Hooft (born 1940), Dutch field hockey player
- Gerard 't Hooft (born 1946), Dutch theoretical physicist and Nobel Laureate
- Jotie T'Hooft (1956–1977), Flemish Belgian neo-romantic poet
;Van Hooft / Van der Hooft
- (born 1941), Dutch Socialist Party politician
- Anna Van Hooft (born 1980s), Canadian actress
- Elroy van der Hooft (born 1990), Dutch football forward
See also
;Named after Pieter Corneliszoon Hooft
- , artificial islet in the IJmeer
- P. C. Hooft Award, Dutch language literary lifetime achievement award
- MV Pieter Corneliszoon Hooft, Dutch ocean liner built in 1925
;Named after Gerard 't Hooft
- 9491 Thooft (without an apostrophe), a main-belt asteroid
- Quantum field theory terminology:
- 't Hooft matching condition
- 't Hooft loop
- 't Hooft symbol
- 't Hooft–Polyakov monopole