Holzwickede () is a municipality in the district of Unna in North Rhine-Westphalia, Germany.
It is twinned with Weymouth, Louviers and Colditz.
Mayors
- 1969–1975: Josef Wortmann
- 1975–1989: Heinrich Schürhoff
- 1989–1999: Margret Mader
- 1999–2015: Jenz Rother
- since 2015: Ulrike Drossel
People from Holzwickede
- Agnes von der Vierbecke ( 1341-1378), commemorated at Dortmund's Pepper Pot Festival
- Julius Bergmann (1839-1904), philosopher
- Hermann Mandel (1882-1946), theologian
- Hermann Strathmann (1882-1966), theologian and politician
- Nils Mönkemeyer (born 1978), violist and academic teacher