The Holy Trinity Cathedral, also known as Holy Trinity Greek Orthodox Church, is a Greek Orthodox cathedral in Salt Lake City, Utah, United States. Built in 1923, the church was listed on the National Register of Historic Places in 1975.

thumb|left|Southwest side view of the Holy Trinity Cathedral, January 2009

The church was a central element of Greek Town in the non-LDS immigrant district of Salt Lake City and served Serbian and Russian immigrants in addition to Greeks.

The church's Byzantine architecture was unusual for the region. Design was by a local architecture firm, Pope and Burton, in collaboration with a Greek architect from Chicago, N. A. Dokas.

Holy Trinity was elevated to the status of a cathedral in 1968 during a visit by Archbishop Iakovos, primate of the Greek Orthodox Archdiocese of America.