thumb|Histologic specimen being placed on the stage of an [[optical microscope]]

right|300px|thumb|Human [[lung tissue stained with hematoxylin and eosin as seen under a microscope]]

Histology, also known as microscopic anatomy, microanatomy is the branch of biology that studies the microscopic anatomy of biological tissues.

Embedding

Tissues are embedded in a harder medium both as a support and to allow the cutting of thin tissue slices.

Staining

Biological tissue has little inherent contrast in either the light or electron microscope.

In the early 1830s Purkynĕ invented a microtome with high precision.

The 1906 Nobel Prize in Physiology or Medicine was awarded to histologists Camillo Golgi and Santiago Ramon y Cajal. They had conflicting interpretations of the neural structure of the brain based on differing interpretations of the same images. Ramón y Cajal won the prize for his correct theory, and Golgi for the silver-staining technique that he invented to make it possible.

See also

  • National Society for Histotechnology
  • Slice preparation

Notes

References

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