Hernando is a common Spanish given name, equivalent to Fernando and the English Ferdinand. It may refer to:
Places
;Argentina
- Hernando, Córdoba
;Canada
- Hernando Island, British Columbia
;United States
- Hernando, Florida
- Hernando County, Florida
- Hernando, Mississippi
People
- Hernando de Soto (economist)
- Hernando de Soto (explorer)
- Hernando de Lerma
- Hernando Cortes, alternate spelling of Hernán Cortés
- Alejandro Hernando (born 1976), Argentine taekwondo practitioner
- Ana María Hernando (born 1959), Argentine visual artist
- Mila Hernando (1957–2017), Spanish diplomat
Horse
- Hernando (horse) (1990-2013), French-trained racehorse, winner of the 1993 Prix du Jockey Club