Heebie-jeebies is a phrase, widely attributed to Billy DeBeck, meaning a feeling of anxiety, apprehension, depression or illness.

Heebie-jeebies or heebie jeebies may also refer to:

  • "Heebie Jeebies" (composition), a 1926 single by Louis Armstrong and his Hot Five
  • "Heeby-Jeebies", a 1956 single by Little Richard
  • "Heebiejeebies", a song on the album Good for You by Aminé featuring Kehlani
  • The Heebee-jeebees, an a capella band from Canada
  • The Hee Bee Gee Bees, a comedy parody of the Bee Gees
  • Heebee Jeebees, a 1927 lost comedy film
  • Heebie Jeebies (film), a 2013 science fiction horror film