Greenspun (Anglicized from ) is a surname. Notable people with the surname include:
- Hank Greenspun (1909–1989), American newspaper publisher, and founder of the Greenspun Corporation
- Philip Greenspun (born 1963), American computer scientist and entrepreneur
- Roger Greenspun, American journalist and film critic
See also
- Greenspan
- Greenspoon
- Greenspun Media Group
- Greenspun's Tenth Rule
- The Greenspun Corporation
- Grinspun
- Grünspan