Great Southern Railway may refer to:

  • Journey Beyond, operator of The Ghan, Indian Pacific and The Overland interstate passenger trains in Australia
  • Main Southern railway line, or Great Southern Railway, in New South Wales, Australia
  • Great Southern Railway (South Gippsland), former railway serving the South Gippsland region in Victoria, Australia
  • Great Southern Railway (Western Australia), railway branch from Northam to Albany in Western Australia
  • Great Southern Railways (Ireland)

See also

  • Great Southern (disambiguation)
  • GSR (disambiguation)
  • Southern Railway (disambiguation)