thumb|right | alt=Black and white Image of the U-461 submarine surfaced at sea | Image of the submarine U-461

German submarine U-488 was a Type XIV supply and replenishment U-boat ("Milchkuh") of Nazi Germany's Kriegsmarine during World War II.

Her keel was laid down on 3 January 1942 by Germaniawerft in Kiel as yard number 557. She was launched on 17 October 1942 and commissioned on 1 February 1943, with Leutnant zur See Erwin Bartke in command. Bartke was promoted to Oberleutnant zur See by February 1944; he was relieved by Oblt.z.S. Bruno Studt.